A “poor man’s” approach to topology optimization of natural convection problems
Sign Up to like & getrecommendations! Published in 2019 at "Structural and Multidisciplinary Optimization"
DOI: 10.1007/s00158-019-02215-9
Abstract: Topology optimization of natural convection problems is computationally expensive, due to the large number of degrees of freedom (DOFs) in the model and its two-way coupled nature. Herein, a method is presented to reduce the… read more here.
Keywords: optimization natural; convection; topology; model ... See more keywords
Adjoint optimization of natural convection problems: differentially heated cavity
Sign Up to like & getrecommendations! Published in 2017 at "Theoretical and Computational Fluid Dynamics"
DOI: 10.1007/s00162-016-0398-5
Abstract: Optimization of natural convection-driven flows may provide significant improvements to the performance of cooling devices, but a theoretical investigation of such flows has been rarely done. The present paper illustrates an efficient gradient-based optimization method… read more here.
Keywords: differentially heated; natural convection; optimization natural; time ... See more keywords
Structural Optimization of the Natural Product: Discovery of Almazoles C-D and Their Derivatives as Novel Antiviral and Anti-phytopathogenic Fungus Agents.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.2c05898
Abstract: Plant diseases seriously affect the growth of crops and the quality and yield of agricultural products. The search for plant-derived pesticide candidates based on natural products is a hot topic of current research. Marine natural… read more here.
Keywords: anti tmv; structural optimization; anti; optimization natural ... See more keywords
Optimization of the Natural Product Calothrixin A to Discover Novel Dual Topoisomerase I and II Inhibitors with Improved Anticancer Activity.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of medicinal chemistry"
DOI: 10.1021/acs.jmedchem.2c00615
Abstract: Calothrixin A (CAA) is a dual Topo I and II inhibitor but exhibits poor antiproliferative activities and water solubility. Herein, a library of novel CAA analogues was synthesized. Among them, compound F16 exhibited superior water… read more here.
Keywords: calothrixin; novel dual; optimization natural; natural product ... See more keywords