Cell Factory Design and Optimization for the Stereoselective Synthesis of Polyhydroxylated Compounds
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DOI: 10.1002/cbic.201700464
Abstract: A synthetic cascade for the transformation of primary alcohols into polyhydroxylated compounds in Escherichia coli, through the in situ preparation of cytotoxic aldehyde intermediates and subsequent aldolase‐mediated C−C bond formation, has been investigated. An enzymatic… read more here.
Keywords: factory design; design optimization; polyhydroxylated compounds; optimization stereoselective ... See more keywords