Articles with "optimization substrate" as a keyword



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Optimization of Substrate‐Analogue Furin Inhibitors

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Published in 2017 at "ChemMedChem"

DOI: 10.1002/cmdc.201700596

Abstract: The proprotein convertase furin is a potential target for drug design, especially for the inhibition of furin‐dependent virus replication. All effective synthetic furin inhibitors identified thus far are multibasic compounds; the highest potency was found… read more here.

Keywords: substrate analogue; optimization substrate; potency; furin inhibitors ... See more keywords