Articles with "optimization tambjamines" as a keyword



Discovery and Optimization of Tambjamines as a Novel Class of Antileishmanial Agents.

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Published in 2024 at "Journal of medicinal chemistry"

DOI: 10.1021/acs.jmedchem.4c00517

Abstract: Leishmaniasis is a neglected tropical disease that is estimated to afflict over 12 million people. Current drugs for leishmaniasis suffer from serious deficiencies, including toxicity, high cost, modest efficacy, primarily parenteral delivery, and emergence of… read more here.

Keywords: novel class; discovery optimization; optimization tambjamines; antileishmanial agents ... See more keywords