In Vitro and In-Eye Comparison of Commercial Pilocarpine Ophthalmic Solution and an Optimized, Reformulated Pilocarpine for Presbyopia Treatment
Sign Up to like & getrecommendations! Published in 2022 at "Ophthalmology and Therapy"
DOI: 10.1007/s40123-022-00482-2
Abstract: Pilocarpine hydrochloride (pilo) ophthalmic solution has traditionally been used for the treatment of glaucoma, with opportunities to improve the tolerability profile experienced by patients. Pilocarpine hydrochloride ophthalmic solution 1.25% (Vuity™, Allergan, an AbbVie company) was… read more here.
Keywords: formulation; vitro; ophthalmic solution; treatment ... See more keywords
Synthesis and optimized formulation for high-capacity manganese fluoride (MnF2) electrodes for lithium-ion batteries
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Fluorine Chemistry"
DOI: 10.1016/j.jfluchem.2019.05.007
Abstract: Abstract Electrochemical activity of poorly conductive metal fluorides in Li-ion batteries is contingent on their nanostructuration to reduce diffusion lengths and increase reaction kinetics. In that regard, we optimize the synthesis and electrode formulation of… read more here.
Keywords: synthesis optimized; ion; optimized formulation; formulation high ... See more keywords
Porous and highly responsive cross-linked β-cyclodextrin based nanomatrices for improvement in drug dissolution and absorption.
Sign Up to like & getrecommendations! Published in 2020 at "Life sciences"
DOI: 10.1016/j.lfs.2020.118931
Abstract: AIMS Aim of the study was to enhance the solubility of Chlorthalidone by developing beta-cyclodextrin cross-linked hydrophilic nanomatrices. MAIN METHODS Nine different formulations were fabricated by free radical polymerization technique. All formulations were characterized through… read more here.
Keywords: cross linked; optimized formulation; drug; solubility ... See more keywords
Flurbiprofen-loaded ethanolic liposome particles for biomedical applications.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of microbiological methods"
DOI: 10.1016/j.mimet.2019.04.001
Abstract: Present study deals with the preparation, characterization and in-vivo evaluation of flurbiprofen loaded ethanolic liposome which provides predetermined and controlled release of drug through a transdermal drug delivery system. Ethanolic liposomes were prepared by using… read more here.
Keywords: flurbiprofen loaded; optimized formulation; ethanolic liposome; loaded ethanolic ... See more keywords
Nanoclay-Based Composite Films for Transdermal Drug Delivery: Development, Characterization, and in silico Modeling and Simulation
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Nanomedicine"
DOI: 10.2147/ijn.s367540
Abstract: Purpose Halloysite nanotubes (HNTs) are a versatile and highly investigated clay mineral due to their natural availability, low cost, strong mechanical strength, biocompatibility, and binding properties. The present work explores its role for retarding and… read more here.
Keywords: optimized formulation; nanoclay based; permeation; drug release ... See more keywords
PREPARATION AND EVALUATION OF FAST DISSOLVING TABLETS OF PITAVASTATIN BY 32 FULL FACTORIAL DESIGN
Sign Up to like & getrecommendations! Published in 2019 at "International Journal of Applied Pharmaceutics"
DOI: 10.22159/ijap.2020v12i1.35678
Abstract: Objective: The objective of the present work was to prepare an optimized, fast dissolving tablet (FDT) of Pitavastatin to increase its dissolution by applying 32full factorial design. Methods: Nine formulations (PF1 to PF9) with all possible… read more here.
Keywords: fast dissolving; factorial design; optimized formulation; drug release ... See more keywords
Development of Olive Oil Containing Phytosomal Nanocomplex for Improving Skin Delivery of Quercetin: Formulation Design Optimization, In Vitro and Ex Vivo Appraisals
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DOI: 10.3390/pharmaceutics15041124
Abstract: The objective of the current work was to fabricate, optimize and assess olive oil/phytosomal nanocarriers to improve quercetin skin delivery. Olive oil/phytosomal nanocarriers, prepared by a solvent evaporation/anti-solvent precipitation technique, were optimized using a Box–Behnken… read more here.
Keywords: optimized formulation; formulation; skin delivery; olive oil ... See more keywords
Optimization of a Mucoadhesive Vaginal Gel Containing Clotrimazole Using a D-Optimal Experimental Design and Multivariate Analysis
Sign Up to like & getrecommendations! Published in 2023 at "Polymers"
DOI: 10.3390/polym15092023
Abstract: The aim of this study was to develop a suitable clotrimazole (CLT)-loaded mucoadhesive vaginal gel (CLT-MVG) for topical applications in vaginal candidiasis. Ten CLT-MVG formulations were prepared, consisting of mixtures of acid polyacrylic (Carbopol 940)… read more here.
Keywords: optimized formulation; formulation; vaginal gel; clt ... See more keywords