High-efficiency prime editing with optimized, paired pegRNAs in plants.
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DOI: 10.1038/s41587-021-00868-w
Abstract: Prime editing (PE) applications are limited by low editing efficiency. Here we show that designing prime binding sites with a melting temperature of 30 °C leads to optimal performance in rice and that using two prime… read more here.
Keywords: high efficiency; editing optimized; optimized paired; prime editing ... See more keywords