Autophagy receptor OPTN (optineurin) regulates mesenchymal stem cell fate and bone-fat balance during aging by clearing FABP3
Sign Up to like & getrecommendations! Published in 2020 at "Autophagy"
DOI: 10.1080/15548627.2020.1839286
Abstract: ABSTRACT Senile osteoporosis (OP) is often concomitant with decreased autophagic activity. OPTN (optineurin), a macroautophagy/autophagy (hereinafter referred to as autophagy) receptor, is found to play a pivotal role in selective autophagy, coupling autophagy with bone… read more here.
Keywords: optn optineurin; bone; autophagy; receptor ... See more keywords
OPTN (optineurin)-mediated selective autophagy prevents neurodegeneration due to herpesvirus infection
Sign Up to like & getrecommendations! Published in 2022 at "Autophagy"
DOI: 10.1080/15548627.2022.2037223
Abstract: ABSTRACT Very little is known about the mechanisms that restrict neurotropic herpesviruses such as herpes simplex virus-1 (HSV-1) from infecting the central nervous system (CNS) and causing widespread death of neurons. Likewise, HSV-1 is thought… read more here.
Keywords: mediated selective; optineurin mediated; infection; neurodegeneration ... See more keywords