Spotlight on Nerves: Portable Multispectral Optoacoustic Imaging of Peripheral Nerve Vascularization and Morphology.
Sign Up to like & getrecommendations! Published in 2022 at "Advanced science"
DOI: 10.1002/advs.202301322
Abstract: Various morphological and functional parameters of peripheral nerves and their vascular supply are indicative of pathological changes due to injury or disease. Based on recent improvements in optoacoustic image quality, the ability of multispectral optoacoustic… read more here.
Keywords: contrast; peripheral nerve; morphology; nerve ... See more keywords
Homogentisic acid-derived pigment as a biocompatible label for optoacoustic imaging of macrophages
Sign Up to like & getrecommendations! Published in 2019 at "Nature Communications"
DOI: 10.1038/s41467-019-13041-4
Abstract: Macrophages are one of the most functionally-diverse cell types with roles in innate immunity, homeostasis and disease making them attractive targets for diagnostics and therapy. Photo- or optoacoustics could provide non-invasive, deep tissue imaging with… read more here.
Keywords: derived pigment; homogentisic acid; acid derived; macrophage ... See more keywords
Optoacoustic Imaging Detects Hormone-Related Physiological Changes of Breast Parenchyma.
Sign Up to like & getrecommendations! Published in 2018 at "Ultraschall in der Medizin"
DOI: 10.1055/a-0628-6248
Abstract: PURPOSE Optoacoustic imaging with ultrasound (OPUS) can assess in-vivo perfusion/oxygenation through surrogate measures of oxy, deoxy and total hemoglobin content in tissues. The primary aim of our study was to evaluate the ability of OPUS… read more here.
Keywords: changes breast; menopausal; repeatability; optoacoustic imaging ... See more keywords
Mapping of neuroinflammation-induced hypoxia in the spinal cord using optoacoustic imaging
Sign Up to like & getrecommendations! Published in 2022 at "Acta Neuropathologica Communications"
DOI: 10.1186/s40478-022-01337-4
Abstract: Recent studies suggest that metabolic changes and oxygen deficiency in the central nervous system play an important role in the pathophysiology of multiple sclerosis (MS). In our present study, we investigated the changes in oxygenation… read more here.
Keywords: eae; mapping neuroinflammation; optoacoustic imaging; hypoxia spinal ... See more keywords
Integrin-targeted quantitative optoacoustic imaging with MRI correlation for monitoring a BRAF/MEK inhibitor combination therapy in a murine model of human melanoma
Sign Up to like & getrecommendations! Published in 2018 at "PLoS ONE"
DOI: 10.1371/journal.pone.0204930
Abstract: Purpose To investigate αvβ3-integrin-targeted optoacoustic imaging and MRI for monitoring a BRAF/MEK inhibitor combination therapy in a murine model of human melanoma. Materials and methods Human BRAF V600E-positive melanoma xenograft (A375)-bearing Balb/c nude mice (n… read more here.
Keywords: braf mek; mek inhibitor; integrin targeted; integrin ... See more keywords
Optoacoustic Imaging in Inflammation
Sign Up to like & getrecommendations! Published in 2021 at "Biomedicines"
DOI: 10.3390/biomedicines9050483
Abstract: Optoacoustic or photoacoustic imaging (OAI/PAI) is a technology which enables non-invasive visualization of laser-illuminated tissue by the detection of acoustic signals. The combination of “light in” and “sound out” offers unprecedented scalability with a high… read more here.
Keywords: technology; imaging inflammation; inflammation; optoacoustic imaging ... See more keywords