Melanopsin for precise optogenetic activation of astrocyte‐neuron networks
Sign Up to like & getrecommendations! Published in 2019 at "Glia"
DOI: 10.1002/glia.23580
Abstract: Optogenetics has been widely expanded to enhance or suppress neuronal activity and it has been recently applied to glial cells. Here, we have used a new approach based on selective expression of melanopsin, a G‐protein‐coupled… read more here.
Keywords: optogenetic activation; melanopsin precise; astrocyte; neuron ... See more keywords
Optogenetic activation of dopamine receptor D1 and D2 neurons in anterior cingulate cortex differentially modulates trigeminal neuropathic pain
Sign Up to like & getrecommendations! Published in 2020 at "Molecular neurobiology"
DOI: 10.1007/s12035-020-02020-2
Abstract: Anterior cingulate cortex (ACC) is a critical brain center for chronic pain processing. Dopamine signaling in the brain has been demonstrated to contribute to descending pain modulation. However, the role of ACC dopamine receptors in… read more here.
Keywords: optogenetic activation; dopamine; neuropathic pain; trigeminal neuropathic ... See more keywords
Optogenetic Activation of Interneuron Subtypes Modulates Visual Contrast Responses of Mouse V1 Neurons.
Sign Up to like & getrecommendations! Published in 2021 at "Cerebral cortex"
DOI: 10.1093/cercor/bhab269
Abstract: Interneurons are critical for information processing in the cortex. In vitro optogenetic studies in mouse primary visual cortex (V1) have sketched the connectivity of a local neural circuit comprising excitatory pyramidal neurons and distinct interneuron… read more here.
Keywords: optogenetic activation; activation interneuron; interneuron subtypes; subtypes modulates ... See more keywords
Optogenetic activation of the superior colliculus attenuates spontaneous seizures in the pilocarpine model of temporal lobe epilepsy
Sign Up to like & getrecommendations! Published in 2022 at "Epilepsia"
DOI: 10.1111/epi.17469
Abstract: Decades of studies have indicated that activation of the deep and intermediate layers of the superior colliculus can suppress seizures in a wide range of experimental models of epilepsy. However, prior studies have not examined… read more here.
Keywords: optogenetic activation; activation superior; model temporal; superior colliculus ... See more keywords
Optogenetic activation of septal inhibitory cells abates focal seizures.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of neurophysiology"
DOI: 10.1152/jn.00111.2023
Abstract: Emerging evidence suggest that the medial septum can control seizures occurring in focal epileptic disorders, thus representing a therapeutic target. Therefore, we investigated whether continuous optogenetic activation of inhibitory parvalbumin-positive (PV) interneurons in the medial… read more here.
Keywords: optogenetic activation; day; medial septum; inhibitory ... See more keywords
Spatiotemporal Control of GPR37 Signaling and Its Behavioral Effects by Optogenetics
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Molecular Neuroscience"
DOI: 10.3389/fnmol.2018.00095
Abstract: Despite the progress in deorphanization of G Protein-Coupled Receptors (GPCRs), ≈100 GPCRs are still classified as orphan receptors without identified endogenous ligands and with unknown physiological functions. The lack of endogenous ligands triggering GPCR signaling… read more here.
Keywords: optogenetic activation; control gpr37; opto gpr37; spatiotemporal control ... See more keywords
Ultrafast (400 Hz) network oscillations induced in mouse barrel cortex by optogenetic activation of thalamocortical axons
Sign Up to like & getrecommendations! Published in 2023 at "eLife"
DOI: 10.7554/elife.82412
Abstract: Oscillations of extracellular voltage, reflecting synchronous, rhythmic activity in large populations of neurons, are a ubiquitous feature in the mammalian brain, and are thought to subserve important, if not fully understood roles in normal and… read more here.
Keywords: optogenetic activation; ultrafast 400; activation thalamocortical; thalamocortical axons ... See more keywords