Optogenetic manipulation of astrocytes from synapses to neuronal networks: A potential therapeutic strategy for neurodegenerative diseases
Sign Up to like & getrecommendations! Published in 2019 at "Glia"
DOI: 10.1002/glia.23693
Abstract: Astrocytes are the most widespread and heterogeneous glial cells in the central nervous system and key regulators for brain development. They are capable of receiving neurotransmitters produced by synaptic activities and regulating synaptic functions by… read more here.
Keywords: therapeutic strategy; neurodegenerative diseases; potential therapeutic; optogenetic manipulation ... See more keywords
A computational model of the respiratory network challenged and optimized by data from optogenetic manipulation of glycinergic neurons
Sign Up to like & getrecommendations! Published in 2017 at "Neuroscience"
DOI: 10.1016/j.neuroscience.2017.01.041
Abstract: The topology of the respiratory network in the brainstem has been addressed using different computational models, which help to understand the functional properties of the system. We tested a neural mass model by comparing the… read more here.
Keywords: manipulation glycinergic; glycinergic neurons; respiratory network; model ... See more keywords
An Upconversion Nanoparticle Enables Near Infrared-Optogenetic Manipulation of the Caenorhabditis elegans Motor Circuit.
Sign Up to like & getrecommendations! Published in 2019 at "ACS nano"
DOI: 10.1021/acsnano.8b09270
Abstract: Near-infrared (NIR) light penetrates tissue deeply, but its application to motor behavior stimulation has been limited by the lack of known genetic NIR light-responsive sensors. We designed and synthesized a Yb3+/Er3+/Ca2+-based lanthanide-doped upconversion nanoparticle (UCNP)… read more here.
Keywords: optogenetic manipulation; near infrared; caenorhabditis elegans; upconversion nanoparticle ... See more keywords
Bioprinting Living Biofilms through Optogenetic Manipulation.
Sign Up to like & getrecommendations! Published in 2018 at "ACS synthetic biology"
DOI: 10.1021/acssynbio.8b00003
Abstract: In this paper, we present a new strategy for microprinting dense bacterial communities with a prescribed organization on a substrate. Unlike conventional bioprinting techniques that require bioinks, through optogenetic manipulation, we directly manipulated the behaviors… read more here.
Keywords: biofilms optogenetic; bioprinting living; biology; living biofilms ... See more keywords