Retrospective analysis of genome sequences revealed the wide dissemination of optrA in Gram-positive bacteria
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Antimicrobial Chemotherapy"
DOI: 10.1093/jac/dkw488
Abstract: Sir, Oxazolidinones, including linezolid and tedizolid, are highly effective against infections of enterococci, staphylococci and streptococci, which are clinically important Gram-positive pathogens. cfr is the first gene that is transferable and causes resistance to oxazolidinones;… read more here.
Keywords: optra; gram positive; sequences revealed; figure ... See more keywords
Presence of optrA-mediated linezolid resistance in multiple lineages and plasmids of Enterococcus faecalis revealed by long read sequencing
Sign Up to like & getrecommendations! Published in 2022 at "Microbiology"
DOI: 10.1099/mic.0.001137
Abstract: Transferable linezolid resistance due to optrA, poxtA, cfr and cfr-like genes is increasingly detected in enterococci associated with animals and humans globally. We aimed to characterize the genetic environment of optrA in linezolid-resistant Enterococcus faecalis… read more here.
Keywords: linezolid resistance; enterococcus faecalis; resistance; long read ... See more keywords