Role of ORAI Proteins in Activation of Endogenous TRPC1-Composed Channels
Sign Up to like & getrecommendations! Published in 2017 at "Biophysical Journal"
DOI: 10.1016/j.bpj.2016.11.2621
Abstract: Depletion of intracellular calcium stores activates store-operated channels. This process induces numerous intracellular signaling events. The most studied store-operated channels are CRAC channels. Other channels are believed to consist of TRPC and Orai proteins. However,… read more here.
Keywords: store operated; proteins activation; role orai; role ... See more keywords
Ca2+ channel-forming ORAI proteins: cancer foes or cancer allies?
Sign Up to like & getrecommendations! Published in 2019 at "Experimental oncology"
DOI: 10.32471/exp-oncology.2312-8852.vol-41-no-3.13473
Abstract: The ORAI family of ion channel-forming proteins in mammals includes three members, ORAI1, ORAI2 and ORAI3, encoded by homologous genes. Of these proteins the ORAI1 one received major attention as plasma membrane constituent of store-operated calcium entry… read more here.
Keywords: orai proteins; channel forming; ca2; entry ... See more keywords