To die or not to die SGK1-sensitive ORAI/STIM in cell survival.
Sign Up to like & getrecommendations! Published in 2018 at "Cell calcium"
DOI: 10.1016/j.ceca.2018.05.001
Abstract: The pore forming Ca2+ release activated Ca2+ channel (CRAC) isoforms ORAI1-3 and their regulators STIM1,2 accomplish store operated Ca2+ entry (SOCE). Activation of SOCE may lead to cytosolic Ca2+ oscillations, which in turn support cell… read more here.
Keywords: cell survival; sgk1 dependent; orai1 stim1; orai stim ... See more keywords
Involvement of calcium regulating ion channels in contractility of human isolated urinary bladder.
Sign Up to like & getrecommendations! Published in 2018 at "General physiology and biophysics"
DOI: 10.4149/gpb_2017064
Abstract: This study specified the role of several key calcium-operating ion channels in contraction/relaxation of human detrusor muscle as possible target for overactive bladder (OAB) treatment. Detrusor samples, obtained from 18 males (average age 61.5 ±… read more here.
Keywords: stim channels; ion channels; bladder; orai stim ... See more keywords