A novel STIM1-Orai1 gating interface essential for CRAC channel activation.
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DOI: 10.1016/j.ceca.2019.02.009
Abstract: Calcium signalling through store-operated calcium (SOC) entry is of crucial importance for T-cell activation and the adaptive immune response. This entry occurs via the prototypic Ca2+ release-activated Ca2+ (CRAC) channel. STIM1, a key molecular component… read more here.
Keywords: orai1 gating; stim1; crac channel; stim1 orai1 ... See more keywords