Orai1 Inhibitors as Potential Treatments for Pulmonary Arterial Hypertension
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DOI: 10.1161/circresaha.122.321041
Abstract: Background: Pulmonary arterial hypertension (PAH) is characterized by progressive distal pulmonary artery (PA) obstruction, leading to right ventricular hypertrophy and failure. Exacerbated intracellular calcium (Ca2+) signaling contributes to abnormalities in PA smooth muscle cells (PASMCs),… read more here.
Keywords: hpasmcs; arterial hypertension; orai1; pulmonary arterial ... See more keywords