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   Articles with "orai1 stim1" as a keyword



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To die or not to die SGK1-sensitive ORAI/STIM in cell survival.

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recommendations! Published in 2018 at "Cell calcium"

DOI: 10.1016/j.ceca.2018.05.001

Abstract: The pore forming Ca2+ release activated Ca2+ channel (CRAC) isoforms ORAI1-3 and their regulators STIM1,2 accomplish store operated Ca2+ entry (SOCE). Activation of SOCE may lead to cytosolic Ca2+ oscillations, which in turn support cell… read more here.

Keywords: cell survival; sgk1 dependent; orai1 stim1; orai stim ... See more keywords
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Evidence for the interaction of peroxiredoxin-4 with the store-operated calcium channel activator STIM1 in liver cells.

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recommendations! Published in 2018 at "Cell calcium"

DOI: 10.1016/j.ceca.2018.05.002

Abstract: Ca2+ entry through store-operated Ca2+ channels (SOCs) in the plasma membrane (PM) of hepatocytes plays a central role in the hormonal regulation of liver metabolism. SOCs are composed of Orai1, the channel pore protein, and… read more here.

Keywords: store operated; orai1 stim1; stim1; activator ... See more keywords
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Inhibition of Lithium Sensitive Orai1/ STIM1 Expression and Store Operated Ca2+ Entry in Chorea-Acanthocytosis Neurons by NF-κB Inhibitor Wogonin

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recommendations! Published in 2018 at "Cellular Physiology and Biochemistry"

DOI: 10.1159/000495229

Abstract: Background/Aims: The neurodegenerative disease Chorea-Acanthocytosis (ChAc) is caused by loss-of-function-mutations of the chorein-encoding gene VPS13A. In ChAc neurons transcript levels and protein abundance of Ca2+ release activated channel moiety (CRAC) Orai1 as well as its… read more here.

Keywords: orai1 stim1; inhibition; expression; lithium ... See more keywords
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Effect of MgCl2 and GdCl3 on ORAI1 Expression and Store-Operated Ca2+ Entry in Megakaryocytes

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recommendations! Published in 2021 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms22073292

Abstract: In chronic kidney disease, hyperphosphatemia upregulates the Ca2+ channel ORAI and its activating Ca2+ sensor STIM in megakaryocytes and platelets. ORAI1 and STIM1 accomplish store-operated Ca2+ entry (SOCE) and play a key role in platelet… read more here.

Keywords: store operated; orai1 stim1; operated ca2; ca2 ... See more keywords