Reservoir Microneedle Patch Mitigates Postsurgical Atrial Fibrillation
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DOI: 10.1002/adfm.202312525
Abstract: Oral amiodarone for 3–6 months is commonly required for the prevention and treatment of atrial fibrillation (AF) after surgical ablation of refractory AF. However, clinical data show that oral administration is likely to cause systemic… read more here.
Keywords: microneedle patch; oral administration; reservoir microneedle; atrial fibrillation ... See more keywords
Acute Oral Administration of Single‐Walled Carbon Nanotubes Increases Intestinal Permeability and Inflammatory Responses: Association with the Changes in Gut Microbiota in Mice
Sign Up to like & getrecommendations! Published in 2018 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.201701313
Abstract: With the increasing production and widespread potential applications of single-walled carbon nanotubes (SWCNTs), the possible impacts of oral administration of SWCNTs on gastrointestinal tract at currently occupational exposure limits and potential biomedical applications should be… read more here.
Keywords: administration; walled carbon; single walled; gut microbiota ... See more keywords
Smart Oral Administration of Polydopamine-Coated Nanodrugs for Efficient Attenuation of Radiation-Induced Gastrointestinal Syndrome.
Sign Up to like & getrecommendations! Published in 2020 at "Advanced healthcare materials"
DOI: 10.1002/adhm.201901778
Abstract: High-dose ionizing radiation can lead to death from the unrecoverable damage of the gastrointestinal tract, especially the small intestine. Until now, the lack of predilection for the small intestine and rapid clearance by digestive fluids… read more here.
Keywords: radiation induced; gastrointestinal syndrome; smart oral; oral administration ... See more keywords
Oral Administration Properties Evaluation of Three Milk‐Derived Extracellular Vesicles Based on Ultracentrifugation Extraction Methods
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DOI: 10.1002/adhm.202401370
Abstract: Milk‐derived extracellular vesicles (M‐EVs) are low‐cost, can be prepared in large quantities, and can cross the gastrointestinal barrier for oral administration. However, the composition of milk is complex, and M‐EVs obtained by different extraction methods… read more here.
Keywords: extraction methods; oral administration; evs; milk ... See more keywords
Phenylbutazone blood and urine concentrations, pharmacokinetics, and effects on biomarkers of inflammation in horses following intravenous and oral administration of clinical doses.
Sign Up to like & getrecommendations! Published in 2019 at "Drug testing and analysis"
DOI: 10.1002/dta.2553
Abstract: Phenylbutazone (PBZ) is a potent mon-steroidal anti-inflammatory drug used commonly in performance horses. The objectives of the current study were to describe blood and urine concentrations and the pharmacokinetics of PBZ and its metabolites following… read more here.
Keywords: administration; urine concentrations; blood urine; concentrations pharmacokinetics ... See more keywords
Use of liquid chromatography‐tandem mass spectrometry for determination of higenamine in urine following oral administration of traditional Chinese medicine
Sign Up to like & getrecommendations! Published in 2022 at "Drug Testing and Analysis"
DOI: 10.1002/dta.3278
Abstract: Abstract Since higenamine (HG) was first included in the World Anti‐doping Agency (WADA) 2017 Prohibited List, an increasing number of plants have been found to contain this ingredient. As a result, doctors are hesitant to… read more here.
Keywords: administration; following oral; chinese medicine; oral administration ... See more keywords
Pharmacokinetics of Ethyl Glucuronide and Ethyl Sulfate and Pharmacodynamic Effects Following Intravenous and Oral Administration of Ethanol to Exercised Horses
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DOI: 10.1002/dta.3803
Abstract: ABSTRACT Ethanol, a central nervous system depressant and banned substance in horseracing, has reportedly been administered to horses prior to competition to “calm a horse's nerves.” In this study, the pharmacokinetics of two metabolites of… read more here.
Keywords: oral administration; administration; administration ethanol; ethyl sulfate ... See more keywords
Rapid characterization of the absorbed chemical constituents of Tangzhiqing formula following oral administration using UHPLC-Q-TOF-MS.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of separation science"
DOI: 10.1002/jssc.201700777
Abstract: Tangzhiqing formula, a Chinese herbal formula, is used for the treatment of type II diabetes and prediabetes. Although its effectiveness has been certified by clinical use, its absorbed chemical constituents are not comprehensively represented. Thence,… read more here.
Keywords: tangzhiqing formula; absorbed chemical; oral administration; chemical constituents ... See more keywords
Acute and chronic effects of oral administration of a medium‐chain fatty acid, capric acid, on locomotor activity and anxiety‐like and depression‐related behaviors in adult male C57BL/6J mice
Sign Up to like & getrecommendations! Published in 2022 at "Neuropsychopharmacology Reports"
DOI: 10.1002/npr2.12226
Abstract: Capric acid (also known as decanoic acid or C10) is one of the fatty acids in the medium‐chain triglycerides (MCTs) commonly found in dietary fats. Although dietary treatment with MCTs is recently of great interest… read more here.
Keywords: medium chain; effects oral; oral administration; capric acid ... See more keywords
Sensor-based algorithmic dosing suggestions for oral administration of levodopa/carbidopa microtablets for Parkinson’s disease: a first experience
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Neurology"
DOI: 10.1007/s00415-019-09183-6
Abstract: ObjectiveDosing schedules for oral levodopa in advanced stages of Parkinson’s disease (PD) require careful tailoring to fit the needs of each patient. This study proposes a dosing algorithm for oral administration of levodopa and evaluates… read more here.
Keywords: dosing suggestions; levodopa; sensor based; parkinson disease ... See more keywords
Oral administration of d-serine prevents the onset and progression of colitis in mice
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Gastroenterology"
DOI: 10.1007/s00535-021-01792-1
Abstract: l-amino acids are the predominant forms of organic molecules on the planet, but recent studies have revealed that various foods contain d-amino acids, the enantiomers of l-amino acids. Though diet plays important roles in both… read more here.
Keywords: amino acids; serine; colitis; mice ... See more keywords