Vorolanib (X-82), an oral anti-VEGFR/PDGFR/CSF1R tyrosine kinase inhibitor, with everolimus in solid tumors: results of a phase I study
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DOI: 10.1007/s10637-021-01093-7
Abstract: Background Anti-vascular endothelial growth factor receptor (VEGFR) tyrosine kinase inhibitors (TKI) combined with mTOR inhibitors, like everolimus, result in significant responses and prolonged progression-free survival (PFS) among patients with renal cell carcinoma (RCC) [1]. However,… read more here.
Keywords: solid tumors; oral anti; anti vegfr; phase study ... See more keywords
Quantity and economic value of unused oral anti‐cancer and biological disease‐modifying anti‐rheumatic drugs among outpatient pharmacy patients who discontinue therapy☆
Sign Up to like & getrecommendations! Published in 2019 at "Research in Social and Administrative Pharmacy"
DOI: 10.1016/j.sapharm.2018.03.064
Abstract: Background: Patients sometimes discontinue the use of expensive oral anti‐cancer drug (OACD) or biological disease‐modifying anti‐rheumatic drug (bDMARD) therapies early, leading to medication waste if the patient has not used all dispensed medication. Objective: To… read more here.
Keywords: oral anti; value; pharmacy; medication ... See more keywords
Effect of anti-coagulation in elderly patients with atrial fibrillation
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DOI: 10.1093/europace/euab116.105
Abstract: Type of funding sources: None. Atrial fibrillation has been shown to associate with greater cognitive decline and increased dementia risk independent of ischaemic stroke. Anti-coagulation was associated with a lower risk of ischemic stroke and… read more here.
Keywords: anti platelet; atrial fibrillation; elderly patients; oral anti ... See more keywords
Oral anti-coagulant treatment patterns in atrial fibrillation patients diagnosed with cancer: A Danish nationwide cohort study.
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DOI: 10.1111/bjh.18060
Abstract: Data on the use of oral anti-coagulants (OAC) for stroke prevention in cancer patients with atrial fibrillation (AF) are sparse. Nationwide cohort study of patients with AF (2012-2018) and an indication for OAC who were… read more here.
Keywords: cancer; doac; treatment; diagnosed cancer ... See more keywords
Efficacy and safety of the direct oral anti-coagulants in patients with cerebral vein thrombosis: A systematic review and meta-analysis.
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DOI: 10.1111/bjh.18177
Abstract: Vitamin K antagonists (VKAs) are the standard oral anti-coagulant treatment for patients with cerebral venous thrombosis (CVT). However, the direct oral anti-coagulants (DOACs) started replacing VKAs also in this setting. We aimed to evaluate safety… read more here.
Keywords: anti; thrombosis; patients studies; treatment ... See more keywords
Rifabutin-Loaded Nanostructured Lipid Carriers as a Tool in Oral Anti-Mycobacterial Treatment of Crohn’s Disease
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DOI: 10.3390/nano10112138
Abstract: Oral anti-mycobacterial treatment of Crohn’s disease (CD) is limited by the low aqueous solubility of drugs, along with the altered gut conditions of patients, making uncommon their clinical use. Hence, the aim of the present… read more here.
Keywords: mycobacterial treatment; anti mycobacterial; crohn disease; oral anti ... See more keywords
Effect of Lifestyle Modification and Oral Anti-Diabetic Drugs on Metabolic Parameters in Recently Diagnosed Patientswith Uncomplicated Type 2 Diabetes Mellitus in Eastern India
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DOI: 10.4236/jdm.2018.82002
Abstract: BACKGROUND: Oral anti-diabetic drugs (OADs) are often advised for initial treatment for patients with Type 2 Diabetes Mellitus (T2DM). Their effects on glycemic control, lipid profile, insulin resistance and beta cell function has not been… read more here.
Keywords: metabolic parameters; oral anti; recently diagnosed; anti diabetic ... See more keywords