Efficacy and safety of three new oral antiviral treatment (molnupiravir, fluvoxamine and Paxlovid) for COVID-19：a meta-analysis
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DOI: 10.1080/07853890.2022.2034936
Abstract: Abstract Background The coronavirus disease (COVID-19) epidemic has not been completely controlled. Although great achievements have been made in COVID-19 research and many antiviral drugs have shown good therapeutic effects against COVID-19, a simple oral… read more here.
Keywords: oral antiviral; molnupiravir fluvoxamine; covid; covid patients ... See more keywords
Adherence and perceived barriers to oral antiviral therapy for chronic hepatitis B
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DOI: 10.1080/16549716.2018.1433987
Abstract: ABSTRACT Background: Globally, of the 248 million people chronically infected with the hepatitis B virus (HBV), 74 million reside in China. Five oral nucleot(s)ide analogs (NUCs) have been approved for the treatment of chronic hepatitis… read more here.
Keywords: hepatitis; oral antiviral; chronic hepatitis; therapy ... See more keywords
AT-527, a Double Prodrug of a Guanosine Nucleotide Analog, Is a Potent Inhibitor of SARS-CoV-2 In Vitro and a Promising Oral Antiviral for Treatment of COVID-19
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DOI: 10.1128/aac.02479-20
Abstract: The impact of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), the causative agent of COVID-19, is global and unprecedented. Although remdesivir has recently been approved by the FDA to treat SARS-CoV-2 infection, no oral antiviral is… read more here.
Keywords: double prodrug; treatment; prodrug guanosine; sars cov ... See more keywords
Assessment of histopathological alterations in patients with chronic hepatitis B infection following long-term oral antiviral therapy
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DOI: 10.15537/smj.2018.10.23056
Abstract: Objectives: To evaluate the histopathological changes in the liver after oral antiviral therapy in patients with chronic hepatitis B. Methods: A total of 79 HBeAg-negative and positive patients who had been on lamivudine, entecavir, or… read more here.
Keywords: antiviral therapy; long term; oral antiviral; patients chronic ... See more keywords
Dispensing of Oral Antiviral Drugs for Treatment of COVID-19 by Zip Code-Level Social Vulnerability - United States, December 23, 2021-May 21, 2022.
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DOI: 10.15585/mmwr.mm7125e1
Abstract: The COVID-19 pandemic has highlighted and exacerbated long-standing inequities in the social determinants of health (1-3). Ensuring equitable access to effective COVID-19 therapies is essential to reducing health disparities. Molnupiravir (Lagevrio) and nirmatrelvir/ritonavir (Paxlovid) are… read more here.
Keywords: vulnerability; social vulnerability; december 2021; may 2022 ... See more keywords
Oral Antiviral Treatment for COVID-19: A Comprehensive Review on Nirmatrelvir/Ritonavir
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DOI: 10.3390/v14112540
Abstract: Despite the rapid development of efficient and safe vaccines against COVID-19, the need to confine the pandemic and treat infected individuals on an outpatient basis has led to the approval of oral antiviral agents. Taking… read more here.
Keywords: oral antiviral; covid comprehensive; covid; antiviral treatment ... See more keywords
Adverse effects of oral antiviral therapy in chronic hepatitis B
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DOI: 10.4254/wjh.v9.i5.227
Abstract: Oral nucleoside/nucleotide analogues (NAs) are currently the backbone of chronic hepatitis B (CHB) infection treatment. They are generally well-tolerated by patients and safe to use. To date, a significant number of patients have been treated… read more here.
Keywords: antiviral therapy; oral antiviral; effects oral; chronic hepatitis ... See more keywords