Ultrasound‐Activated Nanoprobiotic Hydrogel Disrupts the Oral‐Brain Axis to Alleviate Diabetic Periodontitis and Cognitive Decline
Sign Up to like & getrecommendations! Published in 2025 at "Advanced Functional Materials"
DOI: 10.1002/adfm.202511408
Abstract: Diabetes‐associated periodontitis and cognitive dysfunction form a vicious cycle that impairs tissue repair. Polyphenol‐engineered artificial nanoprobiotics using ultrasound‐responsive dihydrocaffeic acid (DA)‐mediated Fe/Zn bimetallic porphyrin MOFs (Fe‐TCPP‐DA‐Zn), integrated into adaptive hydrogels, is developed. This design enables… read more here.
Keywords: oral brain; diabetic periodontitis; periodontitis cognitive; brain ... See more keywords
Probing the oral-brain connection: oral microbiome patterns in a large community cohort with anxiety, depression, and trauma symptoms, and periodontal outcomes
Sign Up to like & getrecommendations! Published in 2024 at "Translational Psychiatry"
DOI: 10.1038/s41398-024-03122-4
Abstract: The role of the oral microbiome in mental health has recently been appreciated within the proposed oral-brain axis. This study examined the structure and composition of the salivary microbiome in a large-scale population-based cohort of… read more here.
Keywords: transformed relative; oral brain; clr transformed; relative abundance ... See more keywords
The oral-brain axis: can periodontal pathogens trigger the onset and progression of Alzheimer’s disease?
Sign Up to like & getrecommendations! Published in 2024 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2024.1358179
Abstract: Alzheimer’s disease (AD) is the most prevalent form of dementia, characterized by a progressive cognitive decline. Sporadic AD, accounting for more than 95% of cases, may arise due to the influence of environmental factors. It… read more here.
Keywords: oral brain; alzheimer disease; disease; brain ... See more keywords
Aquaporin 5 in Alzheimer’s disease: a link between oral and brain pathology?
Sign Up to like & getrecommendations! Published in 2022 at "Neural Regeneration Research"
DOI: 10.4103/1673-5374.361545
Abstract: The involvement of aquaporins (AQPs) in the development of read more here.
Keywords: alzheimer disease; link oral; pathology; oral brain ... See more keywords