Molecular insights into the role of electronic cigarettes in oral carcinogenesis
Sign Up to like & getrecommendations! Published in 2023 at "Critical Reviews in Toxicology"
DOI: 10.1080/10408444.2023.2190764
Abstract: Abstract Electronic cigarette (EC) usage or vaping has seen a significant rise in recent years across various parts of the world. They have been publicized as a safe alternative to smoking; however, this is not… read more here.
Keywords: role; role electronic; molecular insights; insights role ... See more keywords
Dynamic changes of exhaustion features in T cells during oral carcinogenesis.
Sign Up to like & getrecommendations! Published in 2022 at "Cell proliferation"
DOI: 10.1111/cpr.13207
Abstract: OBJECTIVES This study aimed to clarify the dynamic changes of exhaustion features in T cells during oral carcinogenesis. MATERIALS AND METHODS Mice were randomly divided into 4NQO group and control group. The exhaustion features of… read more here.
Keywords: dynamic changes; oral carcinogenesis; group; carcinogenesis ... See more keywords
Abstract 10: Sclareol induces apoptosis and inhibits notch signaling in hamster oral carcinogenesis
Sign Up to like & getrecommendations! Published in 2020 at "Cancer Research"
DOI: 10.1158/1538-7445.am2020-10
Abstract: The Notch signaling pathway is an evolutionarily conserved cell signaling pathway. It plays a central role in cell fate decisions and differentiation. The bioavailability of sclareol has been widely studied due to its anti-carcinogenic and… read more here.
Keywords: sclareol; dmba; sclareol induces; notch signaling ... See more keywords
Moesin Involvement in Oral Carcinogenesis of the Lower Lip.
Sign Up to like & getrecommendations! Published in 2018 at "Anticancer research"
DOI: 10.21873/anticanres.12518
Abstract: BACKGROUND/AIM This study analyzed moesin immunoexpression in 91 lip squamous cell carcinomas and its influence in patients' prognosis. MATERIALS AND METHODS Moesin immunoexpression was evaluated at the invasive tumor front by a semi-quantitative score method.… read more here.
Keywords: moesin involvement; moesin; survival rates; oral carcinogenesis ... See more keywords
Development of a murine model of oral carcinogenesis: an accelerated tool for biomarker and anti-tumour drug discovery
Sign Up to like & getrecommendations! Published in 2022 at "ecancermedicalscience"
DOI: 10.3332/ecancer.2022.1413
Abstract: Oral squamous cell carcinoma (OSCC) is the most common cancer in Pakistani men and the second most common cancer in women. The objective of our study was to devise a novel accelerated murine model of… read more here.
Keywords: model oral; carcinogenesis; oral carcinogenesis; mice ... See more keywords
Porphyromonas gingivalis Promotes 4-Nitroquinoline-1-Oxide-Induced Oral Carcinogenesis With an Alteration of Fatty Acid Metabolism
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2018.02081
Abstract: Microbiota has been widely considered to play a critical role in human carcinogenesis. Human papilloma virus, hepatitis B and C virus, and Helicobacter pylori are implicated in the pathogenesis of cancer of uterine cervix, liver,… read more here.
Keywords: acid metabolism; fatty acid; gingivalis; carcinogenesis ... See more keywords
Identification of a Gene-Expression-Based Surrogate of Genomic Instability during Oral Carcinogenesis
Sign Up to like & getrecommendations! Published in 2022 at "Cancers"
DOI: 10.3390/cancers14030834
Abstract: Simple Summary New personalized cancer prevention strategies may decrease the mortality of oral cancer that can arise from oral potentially malignant disorders (OPMD). A major cancer hallmark is the acquisition of multiple deletions or amplifications… read more here.
Keywords: gin score; oral cancer; expression; oral carcinogenesis ... See more keywords
Role of Hemidesmosomes in Oral Carcinogenesis: A Systematic Review
Sign Up to like & getrecommendations! Published in 2023 at "Cancers"
DOI: 10.3390/cancers15092533
Abstract: Simple Summary Hemidesmosomes are junctional complexes that contribute to the attachment of epithelial cells to the underlying basement membrane. Importantly, detachment from the basement membrane, migration and invasion through the connective tissues represent early steps… read more here.
Keywords: studies discussed; review; systematic review; oral carcinogenesis ... See more keywords
A Novel Preclinical In Vitro 3D Model of Oral Carcinogenesis for Biomarker Discovery and Drug Testing
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24044096
Abstract: This study aimed to develop an in vitro three-dimensional (3D) cell culture model of oral carcinogenesis for the rapid, scalable testing of chemotherapeutic agents. Spheroids of normal (HOK) and dysplastic (DOK) human oral keratinocytes were… read more here.
Keywords: carcinogenesis biomarker; model oral; biomarker discovery; oral carcinogenesis ... See more keywords
Autophagy is positively associated with the accumulation of myeloid-derived suppressor cells in 4-nitroquinoline-1-oxide-induced oral cancer
Sign Up to like & getrecommendations! Published in 2018 at "Oncology Reports"
DOI: 10.3892/or.2018.6747
Abstract: It has previously been demonstrated that autophagy and inflammation act synergistically to promote carcinogenesis. However, the precise roles of autophagy in multistep oral carcinogenesis are still unclear, particularly regarding its association with tumor inflammation. The… read more here.
Keywords: oral cancer; induced oral; autophagy; carcinogenesis ... See more keywords
Serum metabolite profiling of a 4-Nitroquinoline-1-oxide-induced experimental oral carcinogenesis model using gas chromatography-mass spectrometry
Sign Up to like & getrecommendations! Published in 2021 at "PeerJ"
DOI: 10.7717/peerj.10619
Abstract: Background Oral cancer progresses from hyperplastic epithelial lesions through dysplasia to invasive carcinoma. The critical needs in oral cancer treatment are expanding our knowledge of malignant tumour progression and the development of useful approaches to… read more here.
Keywords: gas chromatography; mass spectrometry; model; chromatography mass ... See more keywords