Population pharmacokinetics of intravenous and oral ciprofloxacin in children to optimize dosing regimens.
Sign Up to like & getrecommendations! Published in 2021 at "European journal of clinical pharmacology"
DOI: 10.1007/s00228-021-03174-1
Abstract: PURPOSE This study aimed to characterize pharmacokinetics of intravenous and oral ciprofloxacin in children to optimize dosing scheme. METHODS Children treated with ciprofloxacin were included. Pharmacokinetics were described using non-linear mixed-effect modelling and validated with… read more here.
Keywords: intravenous oral; children optimize; pharmacokinetics intravenous; ciprofloxacin ... See more keywords
Oral ciprofloxacin activity against ceftriaxone-resistant Escherichia coli in an in vitro bladder infection model
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Antimicrobial Chemotherapy"
DOI: 10.1093/jac/dkac402
Abstract: Abstract Objectives Pharmacodynamic profiling of oral ciprofloxacin dosing for urinary tract infections caused by ceftriaxone-resistant Escherichia coli isolates with ciprofloxacin MIC ≥ 0.25 mg/L. Background Urine-specific breakpoints for ciprofloxacin do not exist. However, high urinary concentrations may… read more here.
Keywords: bladder infection; ciprofloxacin; ceftriaxone resistant; model ... See more keywords