Omalizumab as alternative to chronic use of oral corticosteroids in severe asthma.
Sign Up to like & getrecommendations! Published in 2019 at "Respiratory medicine"
DOI: 10.1016/j.rmed.2019.02.003
Abstract: Systemic/oral corticosteroids (OCS) have been used for decades in the management of acute asthma exacerbations and chronically in patients with uncontrolled severe asthma. However, while OCS are effective at treating acute exacerbations, there is only… read more here.
Keywords: severe asthma; asthma; alternative chronic; omalizumab alternative ... See more keywords
Effectiveness of pre-operative oral corticosteroids in reducing pain, trismus and oedema following lower third molar extractions: a systematic review.
Sign Up to like & getrecommendations! Published in 2021 at "British dental journal"
DOI: 10.1038/s41415-021-3165-y
Abstract: Aim To determine if a single pre-operative dose of oral corticosteroids would be effective in reducing pain, trismus and oedema following lower third molar surgical extraction. Secondary outcomes of interest were post-operative complications such as… read more here.
Keywords: pre operative; third molar; oral corticosteroids; lower third ... See more keywords
Oral corticosteroids during pregnancy and offspring risk of congenital heart defects: a nationwide cohort study.
Sign Up to like & getrecommendations! Published in 2019 at "International journal of epidemiology"
DOI: 10.1093/ije/dyz213
Abstract: BACKGROUND Pre-pregnancy diabetes is a strong risk factor for congenital heart defects (CHDs), suggesting a role for glucose in the causal pathway. Oral corticosteroids may cause hyperglycemia and maternal use could affect embryonic heart development.… read more here.
Keywords: pregnancy; heart; study; prevalence ... See more keywords
The efficacy of oral corticosteroids for treatment of Tietze syndrome: A pragmatic randomized controlled trial
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Clinical Pharmacy and Therapeutics"
DOI: 10.1111/jcpt.13810
Abstract: Tietze syndrome is a rare form of chest wall costochondritis with joint swelling which can cause significant chest pain and decline in ability of daily activities. There is no standardized treatment protocol. The aim of… read more here.
Keywords: treatment tietze; tietze syndrome; corticosteroids treatment; efficacy oral ... See more keywords
Randomised controlled trial for the titration of oral corticosteroids using markers of inflammation in severe asthma
Sign Up to like & getrecommendations! Published in 2023 at "Thorax"
DOI: 10.1136/thorax-2021-217865
Abstract: Introduction Biomarkers are used to select biologic therapies for patients with severe asthma, but not to regularly adjust therapy, especially oral corticosteroids (OCS). Objective Our goal was to test the efficacy of an algorithm to… read more here.
Keywords: trial; randomised controlled; controlled trial; severe asthma ... See more keywords
Fractional exhaled nitric oxide is associated with more severe asthma
Sign Up to like & getrecommendations! Published in 2018 at "European Respiratory Journal"
DOI: 10.1183/13993003.congress-2018.pa1099
Abstract: Fractional exhaled nitric oxide (FeNO) levels are used as a marker of airway inflammation. The aim of the present work was to evaluate a possible relationship between FeNO and parameters of asthma control and severity… read more here.
Keywords: exhaled nitric; fractional exhaled; oral corticosteroids; oxide associated ... See more keywords
Patient-reported side effects of oral corticosteroids
Sign Up to like & getrecommendations! Published in 2018 at "European Respiratory Journal"
DOI: 10.1183/13993003.congress-2018.pa3144
Abstract: The toxic side effects of oral corticosteroids (OCS) have long been recognised. The need to show effectiveness of new, expensive, potentially steroid-sparing biological therapies for severe asthma requires objective measurement of steroid-induced complications. Existing questionnaires… read more here.
Keywords: side effects; oral corticosteroids; effects oral; patient ... See more keywords
Perspectives on the Efficacy of Benralizumab for Treatment of Eosinophilic Granulomatosis With Polyangiitis
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.865318
Abstract: Two types of interleukin (IL)-5 antibody biologics, anti-IL-5 antibodies (mepolizumab) and anti-IL-5α receptor antibodies (benralizumab), are indicated for severe asthma. While high-dose mepolizumab is also indicated for EGPA, benralizumab is indicated only for severe asthma.… read more here.
Keywords: egpa benralizumab; efficacy benralizumab; benralizumab treatment; treatment ... See more keywords
Unmet Need for Oral Corticosteroids Use and Exacerbations of Asthma in Primary Care in Taiwan
Sign Up to like & getrecommendations! Published in 2022 at "Biomedicines"
DOI: 10.3390/biomedicines10123253
Abstract: Patients with asthma are treated in primary healthcare facilities (PHCFs) in Taiwan, where the asthma control status associated with acute exacerbation (AE) and use of oral corticosteroids (OCS) and short-acting β2-agonist (SABA) inhalers remains unclear.… read more here.
Keywords: total physicians; physicians reported; asthma control; rescue ocs ... See more keywords
Appropriate use of oral corticosteroids for severe asthma
Sign Up to like & getrecommendations! Published in 2018 at "Medical Journal of Australia"
DOI: 10.5694/mja18.00134
Abstract: Severe asthma represents a significant burden of disease, particularly in high income nations; oral corticosteroids (OCS) remain an important part of the management toolkit for these patients. Corticosteroids are effective at targeting numerous elements of… read more here.
Keywords: use; severe asthma; oral corticosteroids; use oral ... See more keywords