A new polymer-excipient for ethanol-resistant, sustained-release oral dosage forms
Sign Up to like & getrecommendations! Published in 2021 at "Drug Delivery and Translational Research"
DOI: 10.1007/s13346-020-00892-4
Abstract: The use of alcoholic beverages can cause uncontrolled release of drugs from sustained-release solid oral dosage forms and pose severe risks to patient health. The aim of this work was to design a new polymeric… read more here.
Keywords: oral dosage; sustained release; ethanol; excipient ethanol ... See more keywords
A review of in vitro and in vivo methods and their correlations to assess mouthfeel of solid oral dosage forms.
Sign Up to like & getrecommendations! Published in 2020 at "Drug discovery today"
DOI: 10.1016/j.drudis.2020.12.015
Abstract: The oral sensory perception of medicines is an important quality attribute that can influence adherence to medication. A systematic review identified studies reporting both in vitro and in vivo data on the mouthfeel of solid… read more here.
Keywords: vitro vivo; solid oral; oral dosage; mouthfeel ... See more keywords
Suitability of the z-Factor for Dissolution Simulation of Solid Oral Dosage Forms: Potential Pitfalls and Refinements.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of pharmaceutical sciences"
DOI: 10.1016/j.xphs.2020.05.019
Abstract: Parameterization of dissolution profiles for subsequent use in in silico modeling and simulation is a crucial element for the success of extrapolating in vitro to in vivo release from solid oral dosage forms. The z-factor… read more here.
Keywords: solid oral; oral dosage; factor; dosage forms ... See more keywords
Applications of Machine Learning in Solid Oral Dosage Form Development.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of pharmaceutical sciences"
DOI: 10.1016/j.xphs.2021.04.013
Abstract: This review comprehensively summarizes the application of machine learning in solid oral dosage form development over the past three decades. In both academia and industry, machine learning is increasingly applied for multiple preformulation/formulation and process… read more here.
Keywords: machine; machine learning; solid oral; oral dosage ... See more keywords
Hyperthermia-Induced In Situ Drug Amorphization by Superparamagnetic Nanoparticles in Oral Dosage Forms
Sign Up to like & getrecommendations! Published in 2022 at "ACS Applied Materials & Interfaces"
DOI: 10.1021/acsami.2c03556
Abstract: Superparamagnetic iron oxide nanoparticles (SPIONs) generate heat upon exposure to an alternating magnetic field (AMF), which has been studied for hyperthermia treatment and triggered drug release. This study introduces a novel application of magnetic hyperthermia… read more here.
Keywords: celecoxib; amorphization; dosage forms; oral dosage ... See more keywords
Effect of the rheological properties of the liquid carrier on the in vitro swallowing of Solid Oral Dosage Forms.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of texture studies"
DOI: 10.1111/jtxs.12618
Abstract: Solid Oral Dosage Forms (SODF) are the most popular oral drug delivery forms, but they can be difficult to swallow, especially for patients suffering from swallowing disorders. This study investigated the dynamics of different combinations… read more here.
Keywords: solid oral; oral dosage; rheological properties; effect ... See more keywords
Administration of oral dosage forms of medicines to children in a resource limited setting
Sign Up to like & getrecommendations! Published in 2022 at "PLOS ONE"
DOI: 10.1371/journal.pone.0276379
Abstract: Background There are many paediatric specific challenges such as lack of age-appropriate dosage forms, inability of young children to swallow tablets and capsules and poor acceptability, during administration of oral dosage forms of medications to… read more here.
Keywords: medications children; dosage; dosage forms; administration oral ... See more keywords
In situ thermal image analysis of selective laser sintering for oral dosage form manufacturing.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of pharmaceutical and biomedical analysis"
DOI: 10.2139/ssrn.4369321
Abstract: Additive Manufacturing (AM) is a fast-growing approach to produce personalized oral dosage forms. Even though some AM technologies are promising as alternative to conventional compounding with resulting dosage manipulation, they still suffer from a lack… read more here.
Keywords: quality control; dosage; analysis; image analysis ... See more keywords
Preparation and Physicochemical Stability of Liquid Oral Dosage Forms Free of Potentially Harmful Excipient Designed for Pediatric Patients
Sign Up to like & getrecommendations! Published in 2019 at "Pharmaceutics"
DOI: 10.3390/pharmaceutics11040190
Abstract: Dexamethasone, hydrochlorothiazide, spironolactone, and phenytoin are commonly used in neonates, but no age-appropriate formulation containing these active pharmaceutical ingredients (APIs) is commercially available. Thus, pharmaceutical compounding of the liquid oral dosage form is required to… read more here.
Keywords: potentially harmful; oral dosage; dosage forms; dosage ... See more keywords
3D-Printed Fast-Dissolving Oral Dosage Forms via Fused Deposition Modeling Based on Sugar Alcohol and Poly(Vinyl Alcohol)—Preparation, Drug Release Studies and In Vivo Oral Absorption
Sign Up to like & getrecommendations! Published in 2023 at "Pharmaceutics"
DOI: 10.3390/pharmaceutics15020395
Abstract: Three-dimensional printing technology holds marked promise for the pharmaceutical industry and is now under intense investigation. Most research is aimed at a greater efficiency in printing oral dosage forms using powder bed printing or fused… read more here.
Keywords: dosage; dosage forms; drug release; oral dosage ... See more keywords
Treatment of pigs with enrofloxacin via different oral dosage forms – environmental contaminations and resistance development of Escherichia coli
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Veterinary Science"
DOI: 10.4142/jvs.21216
Abstract: Background Antibacterial agents play important roles in the treatment of bacterial infections. However, the development of antimicrobial resistance (AMR) and carry-over of substances into the environment are several problems arising during oral treatment of bacterial… read more here.
Keywords: escherichia coli; development; resistance; oral dosage ... See more keywords