In Silico Modeling and Simulation to Guide Bioequivalence Testing for Oral Drugs in a Virtual Population
Sign Up to like & getrecommendations! Published in 2021 at "Clinical Pharmacokinetics"
DOI: 10.1007/s40262-021-01045-7
Abstract: Model-informed drug discovery and development (MID3) shows great advantages in facilitating drug development. A physiologically based pharmacokinetic model is one of the powerful computational approaches of MID3, and the emerging field of virtual bioequivalence is… read more here.
Keywords: bioequivalence; virtual bioequivalence; oral drugs; silico modeling ... See more keywords
Safety and efficacy characteristics of oral drugs in patients with premature ejaculation: a Bayesian network meta-analysis of randomized controlled trials
Sign Up to like & getrecommendations! Published in 2019 at "International Journal of Impotence Research"
DOI: 10.1038/s41443-019-0146-7
Abstract: Although previous studies have investigated the safety and efficacy characteristics of oral drugs in patients with premature ejaculation (PE), the available results remained inconsistent. Hence, this article was conducted to comprehensively compare the effectiveness of… read more here.
Keywords: oral drugs; safety efficacy; meta analysis; efficacy ... See more keywords
Investigational drugs in phase II clinical trials for moderate to severe plaque psoriasis - potential new treatments on the horizon
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DOI: 10.1080/13543784.2018.1533550
Abstract: ABSTRACT Introduction: Psoriasis is a common immune disorder for which there are many FDA-approved therapies. Older oral drugs had limited efficacy and considerable side effects. Biologics have been a major advance but require self-administered injections,… read more here.
Keywords: investigational drugs; oral drugs; clinical trials; psoriasis ... See more keywords
Oral drugs in the treatment of metastatic colorectal cancer
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DOI: 10.1177/17588359211009001
Abstract: Colorectal cancer (CRC) is one of the most common forms of cancer, with an estimated 1.36 million new cases and almost 700,000 deaths annually. Approximately 21% of patients with CRC have metastatic disease at diagnosis.… read more here.
Keywords: metastatic colorectal; oral drugs; treatment; colorectal cancer ... See more keywords
The ocular adverse effects of oral drugs
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DOI: 10.18773/austprescr.2021.028
Abstract: SUMMARY Some commonly prescribed drugs have ocular adverse effects. Many parts of the eye can be affected by oral drugs. Some ocular adverse effects may be reversed with medical or surgical intervention whereas other drugs… read more here.
Keywords: drugs ocular; oral drugs; ocular adverse; effects oral ... See more keywords