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Published in 2020 at "Prescriber"
DOI: 10.1002/psb.1873
Abstract: Rybelsus (semaglutide) is the first GLP‐1 agonist for the treatment of type 2 diabetes to be available as an oral formulation. This article discusses its properties, efficacy and adverse effects.
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Keywords:
rybelsus oral;
agonist semaglutide;
formulation glp;
glp agonist ... See more keywords
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Published in 2020 at "Internal and Emergency Medicine"
DOI: 10.1007/s11739-020-02538-2
Abstract: The slowness of dripping and the presence of alcohol have been offered/suggested as possible causes for the increased risk of developing dependence to the oral formulation of lormetazepam rather than to other anxiolytic and hypnotic…
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Keywords:
risk;
formulation increase;
increase risk;
oral formulation ... See more keywords
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Published in 2021 at "Microporous and Mesoporous Materials"
DOI: 10.1016/j.micromeso.2021.111394
Abstract: COVID-19 is a rapidly evolving emergency, for which there have been no specific medication found yet. Therefore, it is necessary to find a solution for this ongoing pandemic with the aid of advanced pharmaceutics. What…
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Keywords:
silica;
mesoporous silica;
covid;
solution ... See more keywords
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Published in 2018 at "Acta Pharmacologica Sinica"
DOI: 10.1038/aps.2017.159
Abstract: Among the somatostatin analogues, octreotide (OCT) is the most commonly used in clinic via intravenous or subcutaneous injection to treat various diseases caused by increased secretion of growth hormone, gastrin or insulin. In order to…
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Keywords:
developing oral;
gastric mucosal;
mucosal injury;
pharmacokinetic pharmacodynamic ... See more keywords
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Published in 2017 at "Drug Delivery"
DOI: 10.1080/10717544.2016.1225852
Abstract: Abstract Amphotericin B (AmB) remains the “gold standard” for systemic antifungal therapy, even though new drugs are emerging as the attractive antifungal agents. Since AmB has negligible oral absorption as a consequence of its unfavorable…
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Keywords:
design amphotericin;
antifungal therapy;
amphotericin oral;
oral formulation ... See more keywords
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1
Published in 2022 at "Pharmaceutics"
DOI: 10.3390/pharmaceutics14102073
Abstract: The poor aqueous solubility and/or permeability and thereby limited bioavailability largely restricts the pharmaco-therapeutic implications of potent anticancer drugs such as methotrexate (MTX). Furthermore, MTX’s inherently unstable nature makes it difficult to develop a viable…
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Keywords:
mtx;
bioavailability;
aqueous solubility;
permeability ... See more keywords