Oral fosfomycin activity against Klebsiella pneumoniae in a dynamic bladder infection in vitro model
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Antimicrobial Chemotherapy"
DOI: 10.1093/jac/dkac045
Abstract: Abstract Introduction The use of oral fosfomycin for urinary tract infections (UTIs) caused by non-Escherichia coli uropathogens is uncertain, including Klebsiella pneumoniae, the second most common uropathogen. Methods A multicompartment bladder infection in vitro model… read more here.
Keywords: fosfomycin; klebsiella pneumoniae; oral fosfomycin; bladder infection ... See more keywords
1526. Oral Fosfomycin Use for Urinary Tract Infections and Its Clinical Impact on Hospital Stay
Sign Up to like & getrecommendations! Published in 2018 at "Open Forum Infectious Diseases"
DOI: 10.1093/ofid/ofy210.1355
Abstract: Abstract Background Oral fosfomycin is a treatment option for urinary tract infections (UTI) caused by multi-drug-resistant organisms (MDRO). The objective of the study was to describe the prescribing pattern of fosfomycin and determine its role… read more here.
Keywords: urinary tract; use; fosfomycin use; tract infections ... See more keywords
Oral Fosfomycin Efficacy with Variable Urinary Exposures following Single and Multiple Doses against Enterobacterales: the Importance of Heteroresistance for Growth Outcome
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DOI: 10.1128/aac.01982-19
Abstract: Oral fosfomycin trometamol is licensed as a single oral dose for the treatment of uncomplicated urinary tract infections, with activity against multidrug-resistant uropathogens. The impact of interindividual variability in urinary concentrations on antimicrobial efficacy, and… read more here.
Keywords: urinary exposures; efficacy; multiple doses; fosfomycin ... See more keywords
Efficacy and Safety of Oral Fosfomycin-Trometamol in Male Urinary Tract Infections with Multidrug-Resistant Enterobacterales
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DOI: 10.3390/antibiotics11020198
Abstract: Background: Antimicrobial drugs to treat male urinary tract infection (UTI) with multidrug-resistant Enterobacterales are limited. We studied oral fosfomycin-trometamol (FT) in this situation. The objective was to assess the clinical cure rate in patients presenting… read more here.
Keywords: oral fosfomycin; male urinary; resistant enterobacterales; urinary tract ... See more keywords