Articles with "oral histone" as a keyword



Photo by aaronburden from unsplash

A randomized, double‐blind, phase II study of oral histone deacetylase inhibitor resminostat plus S‐1 versus placebo plus S‐1 in biliary tract cancers previously treated with gemcitabine plus platinum‐based chemotherapy

Sign Up to like & get
recommendations!
Published in 2021 at "Cancer Medicine"

DOI: 10.1002/cam4.3813

Abstract: Effective second‐line chemotherapy options are limited in treating advanced biliary tract cancers (BTCs). Resminostat is an oral histone deacetylase inhibitor. Such inhibitors increase sensitivity to fluorouracil, the active form of S‐1. In the phase I… read more here.

Keywords: biliary tract; resminostat; study; histone deacetylase ... See more keywords