Articles with "oral hydroxyurea" as a keyword



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A randomised double-blind placebo-controlled clinical trial of oral hydroxyurea for transfusion-dependent β-thalassaemia

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Published in 2022 at "Scientific Reports"

DOI: 10.1038/s41598-022-06774-8

Abstract: Hydroxyurea is an antimetabolite drug that induces fetal haemoglobin in sickle cell disease. However, its clinical usefulness in β-thalassaemia is unproven. We conducted a randomised, double-blind, placebo-controlled clinical trial to evaluate the efficacy and safety… read more here.

Keywords: transfusion dependent; dependent thalassaemia; transfusion; oral hydroxyurea ... See more keywords