Oral Immunization of FMDV Vaccine Using pH-Sensitive and Mucoadhesive Thiolated Cellulose Acetate Phthalate Microparticles
Sign Up to like & getrecommendations! Published in 2017 at "Tissue Engineering and Regenerative Medicine"
DOI: 10.1007/s13770-017-0082-x
Abstract: Several barriers such as gastric pH, enzymatic degradation and rapid transit should be overcome to orally deliver antigens for taking up by epithelial microfold cells in Peyer’s patches of small intestine. To solve the above… read more here.
Keywords: oral immunization; sensitive mucoadhesive; cellulose acetate; acetate phthalate ... See more keywords
Exploiting or overcoming the dome trap for enhanced oral immunization and drug delivery
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Controlled Release"
DOI: 10.1016/j.jconrel.2018.02.021
Abstract: &NA; The microfold cells (M cells) residing in the outmost follicle‐associated epithelia (FAE) of Peyer's patches capture foreign particles and hand over to sub‐FAE lymphatics, where the particles are retained and disposed subsequently. A concept… read more here.
Keywords: drug delivery; oral immunization; dome trap;
Oral immunization of mice with a multivalent therapeutic subunit vaccine protects against Helicobacter pylori infection.
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DOI: 10.1016/j.vaccine.2020.02.036
Abstract: Helicobacter pylori is a human class I carcinogen and no effective prophylactic or therapeutic H. pylori vaccine has yet been marketed. H. pylori can escape the host immune response, but the precise immune protection mechanisms… read more here.
Keywords: vaccine; oral immunization; subunit; helicobacter pylori ... See more keywords
Upregulation of CD4+CD8+ memory cells in the piglet intestine following oral administration of Bacillus subtilis spores combined with PEDV whole inactivated virus.
Sign Up to like & getrecommendations! Published in 2019 at "Veterinary microbiology"
DOI: 10.1016/j.vetmic.2019.06.003
Abstract: Oral immunization is a commonly employed route for inducing local immunity. However, the application of oral immunization is limited by the short-term persistence of immunity, particularly for inactivated viruses. The ultimate goal for mucosal vaccination… read more here.
Keywords: cd8 memory; pedv wiv; memory; cd4 cd8 ... See more keywords
Lactococcus lactis FNBPA+ (pValac:e6ag85a) Induces Cellular and Humoral Immune Responses After Oral Immunization of Mice
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2021.676172
Abstract: The development of a new vaccine strategy against tuberculosis is urgently needed and has been greatly encouraged by the scientific community worldwide. In this work, we constructed a lactococcal DNA vaccine based on the fusion… read more here.
Keywords: pvalac e6ag85a; oral immunization; immunization mice; fnbpa pvalac ... See more keywords