Chronic shisha exposure alters phosphoproteome of oral keratinocytes
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cell Communication and Signaling"
DOI: 10.1007/s12079-019-00528-4
Abstract: Shisha smoking has been epidemiologically linked to oral cancer. However, few studies have investigated the pathobiology of shisha-induced cellular transformation. We studied the effects of chronic shisha exposure (8 months) in an in vitro model… read more here.
Keywords: shisha exposure; oral keratinocytes; okf6 tert1; chronic shisha ... See more keywords
Filifactor alocis collagenase can modulate apoptosis of normal oral keratinocytes
Sign Up to like & getrecommendations! Published in 2017 at "Molecular Oral Microbiology"
DOI: 10.1111/omi.12163
Abstract: To successfully colonize host cells, pathogenic bacteria must circumvent the host's structural barrier such as the collagen-rich extracellular matrix (ECM), as a preliminary step to invasion and colonization of the periodontal tissue. Filifactor alocis possesses… read more here.
Keywords: normal oral; apoptosis normal; collagenase; oral keratinocytes ... See more keywords
ADAM17 regulates TNF-α expression upon lipopolysaccharide stimulation in oral keratinocytes.
Sign Up to like & getrecommendations! Published in 2017 at "Biomedical research"
DOI: 10.2220/biomedres.38.157
Abstract: A disintegrin and metalloprotease 17 (ADAM17) is a tumor necrosis factor (TNF)-converting enzyme and was first identified as the enzyme that cleaves the prodomain of TNF-α, a proinflammatory cytokine that plays a central role in… read more here.
Keywords: tnf expression; adam17; regulates tnf; oral keratinocytes ... See more keywords
Extracellular Prostaglandins E1 and E2 and Inflammatory Cytokines Are Regulated by the Senescence Program in Potentially Premalignant Oral Keratinocytes
Sign Up to like & getrecommendations! Published in 2022 at "Cancers"
DOI: 10.3390/cancers14112636
Abstract: Potentially pre-malignant lesions (PPOLs) are composed of keratinocytes that are either mortal (MPPOL) or immortal (IPPOL) in vitro. We report here that MPPOL, but not generally IPPOL keratinocytes upregulate various extracellular tumor promoting cytokines (interleukins… read more here.
Keywords: senescence program; premalignant oral; senescence; oral keratinocytes ... See more keywords