Association between oral metformin use and the risk of age-related macular degeneration: A systematic review with meta-analysis.
Sign Up to like & getrecommendations! Published in 2023 at "Acta ophthalmologica"
DOI: 10.1111/aos.15655
Abstract: Rodent studies demonstrate that oral metformin use may reduce chronic low-grade inflammation, downregulate apoptosis and extend life span. Emerging epidemiological evidence suggests that oral metformin use may protect against development of age-related macular degeneration (AMD)… read more here.
Keywords: metformin; risk; oral metformin; association ... See more keywords
Pilot study of oral metformin in cancer‐bearing cats
Sign Up to like & getrecommendations! Published in 2017 at "Veterinary and Comparative Oncology"
DOI: 10.1111/vco.12169
Abstract: A prospective dose escalation pilot study was performed in cancer-bearing cats to assess toxicity and surrogate biomarkers of pharmacologic activity of oral metformin hydrochloride. Nine cats with measurable spontaneous cancer were treated with oral metformin… read more here.
Keywords: oral metformin; pilot study; metformin; cancer bearing ... See more keywords
Metformin improves FOXP3 mRNA expression through suppression of interferon gamma levels in pristane-induced murine models of lupus.
Sign Up to like & getrecommendations! Published in 2020 at "F1000Research"
DOI: 10.12688/f1000research.23471.1
Abstract: Background: A recent study has indicated the potential of metformin therapy for lupus in animal models, but there has been no study evaluating the effect on pristane-induced lupus. This study aims to evaluate the effect… read more here.
Keywords: oral metformin; foxp3 mrna; mrna expression; pristane induced ... See more keywords