Nanoparticle modification in biological media: implications for oral nanomedicines
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DOI: 10.1039/c9ra08403g
Abstract: Nanomedicines undergo transformation in biological media, which impacts biological effects. Such transformation in the gut environment has implications in use of nanomedicines for oral administration. read more here.
Keywords: oral nanomedicines; media implications; modification biological; biological media ... See more keywords
Oral Nanomedicines for siRNA Delivery to Treat Inflammatory Bowel Disease
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DOI: 10.3390/pharmaceutics14091969
Abstract: RNA interference (RNAi) therapies have significant potential for the treatment of inflammatory bowel diseases (IBD). Although administering small interfering RNA (siRNA) via an oral route is desirable, various hurdles including physicochemical, mucus, and cellular uptake… read more here.
Keywords: inflammatory bowel; oral nanomedicines; delivery; sirna delivery ... See more keywords