Combined LRRK2 mutation, aging and chronic low dose oral rotenone as a model of Parkinson’s disease
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DOI: 10.1038/srep40887
Abstract: Aging, genetics and environmental toxicity are important etiological factors in Parkinson’s disease (PD). However, its pathogenesis remains unclear. A major obstacle is the lack of an appropriate experimental model which incorporates genetic susceptibility, aging and… read more here.
Keywords: oral rotenone; rotenone; toxicity; model ... See more keywords
Non-Reproducibility of Oral Rotenone as a Model for Parkinson’s Disease in Mice
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms232012658
Abstract: Oral rotenone has been proposed as a model for Parkinson’s disease (PD) in mice. To establish the model in our lab and study complex behavior we followed a published treatment regimen. C57BL/6 mice received 30… read more here.
Keywords: model parkinson; parkinson disease; disease mice; oral rotenone ... See more keywords