Optimization of an intra-oral solid-phase microextraction (SPME) combined with comprehensive two-dimensional gas chromatography-time-of-flight mass spectrometry (GC × GC-TOFMS) method for oral aroma compounds monitoring of Baijiu.
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DOI: 10.1016/j.foodchem.2022.132502
Abstract: The ''after-odor" is essential to the quality and consumer preference of Baijiu. An intra-oral solid-phase microextraction (SPME) combined with comprehensive two-dimensional gas chromatography-time-of-flight mass spectrometry (GC × GC-TOFMS) was developed for oral aroma compounds monitoring of Baijiu.… read more here.
Keywords: time; aroma compounds; intra oral; aroma ... See more keywords
Development of ezetimibe eutectic with improved biopharmaceutical and mechanical properties to design an optimized oral solid dosage formulation
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DOI: 10.1080/10837450.2022.2143525
Abstract: Abstract Eutectics are multicomponent systems which are an alternative to the conventional techniques for modulating the biopharmaceutical properties of a pharmaceutical. Ezetimibe (ETZ) is a hypocholesterolemic agent with limited dissolution, poor water solubility, and subsequently… read more here.
Keywords: formulation; solid dosage; etz; mechanical properties ... See more keywords
Preliminary Study on the Development of Caffeine Oral Solid Form 3D Printed by Semi-Solid Extrusion for Application in Neonates
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DOI: 10.1208/s12249-023-02582-z
Abstract: Apnea of prematurity can be treated with a body-weight-adjusted dosage of caffeine. Semi-solid extrusion (SSE) 3D printing represents an interesting approach to finely tailor personalized doses of active ingredients. To improve compliance and ensure the… read more here.
Keywords: semi solid; solid extrusion; extrusion; form ... See more keywords
Formulation Strategies to Improve the Stability and Handling of Oral Solid Dosage Forms of Highly Hygroscopic Pharmaceuticals and Nutraceuticals
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DOI: 10.3390/pharmaceutics14102015
Abstract: Highly hygroscopic pharmaceutical and nutraceutical solids are prone to significant changes in their physicochemical properties due to chemical degradation and/or solid-state transition, resulting in adverse effects on their therapeutic performances and shelf life. Moisture absorption… read more here.
Keywords: formulation strategies; highly hygroscopic; solid dosage; hygroscopic pharmaceuticals ... See more keywords