Detection and Characterization of an Unknown Impurity in Levothyroxine Oral Solution Product: Implications for Formulation Development and Storage.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of pharmaceutical sciences"
DOI: 10.1016/j.xphs.2020.09.054
Abstract: An existing USP(2010) impurity method for levothyroxine drug substance was modified to expand its applicability for the analysis of levothyroxine oral solution (OS) formulation while achieving desirable resolution between the components of OS formulation. When… read more here.
Keywords: oral solution; levothyroxine oral; formulation; unknown impurity ... See more keywords
Armillariella Oral Solution Ameliorates Small Intestinal Damage in a Mouse Model of Chemotherapy-Induced Mucositis
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DOI: 10.1080/01635581.2019.1599029
Abstract: Abstract Background: Armillariella oral solution (AOS) shows therapeutic effect on gastrointestinal disorders. We aimed to investigate the potential efficacy of AOS on chemotherapy-induced intestinal mucositis in mice. Methods: Intestinal mucositis was induced in C57BL/6 mice… read more here.
Keywords: mucositis; armillariella oral; oral solution; intestinal mucositis ... See more keywords
Determination of Related Substances in Promethazine Hydrochloride and Dextromethorphan Hydrobromide in Oral Solution by RP-HPLC Method.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of chromatographic science"
DOI: 10.1093/chromsci/bmad039
Abstract: The goal of this study is to provide a single, widely applicable high-performance liquid chromatographic (HPLC) technique for the determination of related substances in multicomponent oral solution of promethazine hydrochloride and dextromethorphan hydrobromide. For the… read more here.
Keywords: promethazine hydrochloride; hplc; dextromethorphan hydrobromide; hydrochloride dextromethorphan ... See more keywords
Ocoxin Oral Solution Exerts an Antitumoral Effect in Pancreatic Cancer and Reduces the Stromal-Mediated Chemoresistance
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DOI: 10.1097/mpa.0000000000001277
Abstract: Objectives Pancreatic carcinoma is one of the most aggressive cancers overcoming chemoresistance. Thus, novel compounds to complement the current antitumor agents are in need. Ocoxin oral solution (OOS) has proven antioxidant, anti-inflammatory, and antistromagenic properties.… read more here.
Keywords: chemoresistance; ocoxin oral; oral solution; effect ... See more keywords
Pharmacokinetics of single and repeated oral doses of pregabalin oral solution formulation in cats
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Veterinary Pharmacology and Therapeutics"
DOI: 10.1111/jvp.13061
Abstract: Abstract The study was designed to determine the pharmacokinetic profile and bioavailability of a novel pregabalin 50 mg/ml oral solution formulation (Bonqat®, Orion Corporation Orion Pharma) in 6 healthy laboratory cats. The cats received pregabalin as… read more here.
Keywords: oral doses; solution formulation; solution; pregabalin oral ... See more keywords
Topical sirolimus: Difference between compounded preparations and commercial oral solution
Sign Up to like & getrecommendations! Published in 2021 at "Pediatric Dermatology"
DOI: 10.1111/pde.14637
Abstract: Topical sirolimus has become a crucial treatment option for many dermatologic disorders. Because an FDA‐approved topical formulation is not commercially available, sirolimus creams, ointments, and gels are professionally prepared by compounding pharmacies. Also, the topical… read more here.
Keywords: topical sirolimus; oral solution; compounded preparations; sirolimus ... See more keywords
Changes of Serum Ferritin, Hemoglobin, and Serum Iron (SI) and Treatment Effect of Iron Proteinsuccinylate Oral Solution Combined with Vitamin A and D Drops on Children with Nutritional Iron Deficiency Anemia
Sign Up to like & getrecommendations! Published in 2022 at "BioMed Research International"
DOI: 10.1155/2022/2972617
Abstract: Objective The purpose was to evaluate the treatment effect of iron proteinsuccinylate oral solution combined with vitamin A and D drops on children with nutritional iron deficiency anemia. Methods 124 children treated in the outpatient… read more here.
Keywords: iron; vitamin drops; group; treatment ... See more keywords
Phase II Trial of Alisertib in Combination with Irinotecan and Temozolomide for Patients with Relapsed or Refractory Neuroblastoma
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DOI: 10.1158/1078-0432.ccr-18-1381
Abstract: Purpose: In phase I testing, alisertib tablets with irinotecan and temozolomide showed significant antitumor activity in patients with neuroblastoma. This study sought to confirm activity of this regimen; evaluate an alisertib oral solution; and evaluate… read more here.
Keywords: phase; oral solution; trial alisertib; irinotecan temozolomide ... See more keywords
Diclofenac potassium for oral solution (CAMBIA®) in the acute management of a migraine attack: clinical evidence and practical experience
Sign Up to like & getrecommendations! Published in 2017 at "Therapeutic Advances in Neurological Disorders"
DOI: 10.1177/1756285616684494
Abstract: Migraine headache affects about 12% of Western populations and is the third most common disease worldwide (sixth in terms of disability). In 1993, triptans were introduced in the United States as a new treatment for… read more here.
Keywords: migraine; oral solution; potassium oral; diclofenac potassium ... See more keywords
Treatment of Congenital Hypothyroidism: Comparison Between L-Thyroxine Oral Solution and Tablet Formulations up to 3 years of age.
Sign Up to like & getrecommendations! Published in 2021 at "European journal of endocrinology"
DOI: 10.1530/eje-20-1444
Abstract: OBJECTIVE Oral solution and tablet formulations of Levo-Thyroxine (L-T4) are both used in the treatment of Congenital Hypothyroidism (CH). However, few studies and with a limited follow-up period have been published comparing these two formulations… read more here.
Keywords: years age; tablet; treatment; oral solution ... See more keywords
Multiple Dose Pharmacokinetics of Tapentadol Oral Solution for the Treatment of Moderate to Severe Acute Pain in Children Aged 2 to
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Pain Research"
DOI: 10.2147/jpr.s364902
Abstract: Background This prospective, open-label trial was conducted to fulfil a post-approval commitment made to the competent authorities to extend the indication of the strong opioid analgesic tapentadol hydrochloride oral solution (OS) to the pediatric population.… read more here.
Keywords: trial; pain; model; tapentadol ... See more keywords