Gene signature predicting recurrence in oral squamous cell carcinoma is characterized by increased oxidative phosphorylation
Sign Up to like & getrecommendations! Published in 2022 at "Molecular Oncology"
DOI: 10.1002/1878-0261.13328
Abstract: Although numerous studies have used systemic approaches to identify prognostic predictors in oral squamous cell carcinoma (OSCC), the effectiveness of these approaches has not been assessed clinically. Further, the mechanism underlying malignant behaviors in OSCC… read more here.
Keywords: cell carcinoma; oxidative phosphorylation; squamous cell; gene signature ... See more keywords
Long noncoding RNA MEG3 inhibits oral squamous cell carcinoma progression via GATA3
Sign Up to like & getrecommendations! Published in 2022 at "FEBS Open Bio"
DOI: 10.1002/2211-5463.13532
Abstract: Oral squamous cell carcinoma (OSCC) accounts for about 90% of oral cancers. Expression of the long noncoding RNA (lncRNA) maternally expressed 3 (MEG3) has previously been reported to be downregulated in OSCC, and its overexpression… read more here.
Keywords: cell carcinoma; squamous cell; long noncoding; gata3 ... See more keywords
Cholesterol Metabolism Modulation Nanoplatform Improves Photo-Immunotherapeutic Effect In Oral Squamous Cell Carcinoma.
Sign Up to like & getrecommendations! Published in 2023 at "Advanced healthcare materials"
DOI: 10.1002/adhm.202300018
Abstract: Impressive results in cancer treatment have been obtained through immunotherapy. However, abnormally high cholesterol metabolism in the tumor microenvironment (TME) leads to poor immunogenicity or even immunosuppression, which dramatically reduces the clinical response of patients… read more here.
Keywords: cell; cholesterol metabolism; squamous cell; oral squamous ... See more keywords
The role of non‐coding RNAs in drug resistance of oral squamous cell carcinoma and therapeutic potential
Sign Up to like & getrecommendations! Published in 2021 at "Cancer Communications"
DOI: 10.1002/cac2.12194
Abstract: Oral squamous cell carcinoma (OSCC), the eighth most prevalent cancer in the world, arises from the interaction of multiple factors including tobacco, alcohol consumption, and betel quid. Chemotherapeutic agents such as cisplatin, 5‐fluorouracil, and paclitaxel… read more here.
Keywords: drug; drug resistance; resistance oscc; oral squamous ... See more keywords
Long noncoding RNA UCA1 promotes cell growth, migration, and invasion by targeting miR‐143‐3p in oral squamous cell carcinoma
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DOI: 10.1002/cam4.2808
Abstract: The long noncoding RNA (lncRNA) urothelial carcinoma‐associated 1 (UCA1) is dysregulated in many types of tumors; however, its role in oral squamous cell carcinoma (OSCC) remains unclear. This study aims to determine the effect of… read more here.
Keywords: long noncoding; carcinoma; oral squamous; squamous cell ... See more keywords
Multiperspective quantitative tumor-stroma ratio reveals histological areas associated with poor outcomes in oral squamous cell carcinoma.
Sign Up to like & getrecommendations! Published in 2023 at "Cancer medicine"
DOI: 10.1002/cam4.5909
Abstract: AIMS Different regions of oral squamous cell carcinoma (OSCC) have particular histopathological characteristics, and the individual histological characteristics of the tumors are poorly understood. Therefore, calculating the proportion of tumor cells in different regions that… read more here.
Keywords: inner tumor; cell carcinoma; squamous cell; oral squamous ... See more keywords
Sentinel node-assisted neck dissection in advanced oral squamous cell carcinoma-A new protocol for staging and treatment.
Sign Up to like & getrecommendations! Published in 2023 at "Cancer medicine"
DOI: 10.1002/cam4.5966
Abstract: BACKGROUND Sentinel lymph node biopsy (SLNB) is used to improve the staging of and guide treatment in patients with early-stage T1-T2 N0 oral squamous cell carcinoma (OSCC). The role of sentinel nodes (SNs) and the use… read more here.
Keywords: cell carcinoma; sentinel; squamous cell; oral squamous ... See more keywords
Gender and risk‐taking behaviors influence the clinical presentation of oral squamous cell carcinoma
Sign Up to like & getrecommendations! Published in 2022 at "Clinical and Experimental Dental Research"
DOI: 10.1002/cre2.523
Abstract: The common risk factors for oral squamous cell carcinoma (OSCC) are smoking and alcohol abuse. A small percentage of patients, mostly women, are demonstrating oral cancer without the common risk behavior. This study investigates how… read more here.
Keywords: risk; influence clinical; oral squamous; cell carcinoma ... See more keywords
Recombinant Porphyromonas gingivalis W83 FimA alters immune response and metabolic gene expression in oral squamous carcinoma cells
Sign Up to like & getrecommendations! Published in 2022 at "Clinical and Experimental Dental Research"
DOI: 10.1002/cre2.588
Abstract: The Gram‐negative anaerobic rod Porphyromonas gingivalis (P. gingivalis) is regarded as a keystone pathogen in periodontitis and expresses a multitude of virulence factors iincluding fimbriae that are enabling adherence to and invasion in cells and… read more here.
Keywords: expression oral; immune response; gene expression; porphyromonas gingivalis ... See more keywords
Upregulated LOX and increased collagen content associated with aggressive clinicopathological features and unfavorable outcome in oral squamous cell carcinoma
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.28669
Abstract: Collagen is a core protein that maintains the homeostasis of the extracellular matrix (ECM), and its dysregulation in human cancers has attracted increasing attention. In tumors, increased lysyl oxidase (LOX)‐catalyzed collagen cross‐linking plays a critical… read more here.
Keywords: collagen; cell carcinoma; oral squamous; squamous cell ... See more keywords
LncRNA PAPAS promotes oral squamous cell carcinoma by upregulating transforming growth factor‐β1
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.28893
Abstract: PAPAS is a recently identified long noncoding RNA (lncRNA) with inhibitory effects on ribosomal RNA synthesis. We studied the role of PAPAS in oral squamous cell carcinoma (OSCC). In the present study we showed that… read more here.
Keywords: transforming growth; cell carcinoma; squamous cell; oral squamous ... See more keywords