Riluzole Oral Suspension: Bioavailability Following Percutaneous Gastrostomy Tube-modeled Administration Versus Direct Oral Administration.
Sign Up to like & getrecommendations! Published in 2019 at "Clinical therapeutics"
DOI: 10.1016/j.clinthera.2019.09.016
Abstract: PURPOSE During amyotrophic lateral sclerosis progression, up to 85% of patients develop dysphagia. Riluzole oral suspension 50 mg/10 mL is bioequivalent to riluzole 50-mg film-coated tablets administered orally under fasting conditions. Here, we compare the bioavailability… read more here.
Keywords: administration; tube; riluzole oral; bioavailability ... See more keywords
Relative Bioavailability and Food Effect Study of an Oral Suspension of Alectinib in Healthy Volunteers Using Venipuncture and Capillary Microsampling.
Sign Up to like & getrecommendations! Published in 2023 at "Clinical and translational science"
DOI: 10.1111/cts.13515
Abstract: Alectinib, approved as 150 mg capsules for the treatment of adults with advanced ALK-positive non-small-cell lung cancer, is being assessed in children with ALK-positive solid and central nervous system tumors. An ad hoc pediatric-friendly suspension… read more here.
Keywords: relative bioavailability; suspension alectinib; capsule; suspension ... See more keywords
Antifungal prophylaxis with posaconazole tablet and oral suspension in patients with haematologic malignancy: Therapeutic drug monitoring, efficacy and risk factors for the suboptimal level
Sign Up to like & getrecommendations! Published in 2019 at "Mycoses"
DOI: 10.1111/myc.13020
Abstract: Posaconazole is used to prevent invasive fungal infections (IFIs) in patients with haematologic malignancy. In this study, we compared plasma posaconazole concentrations (PPCs) and the incidence of breakthrough IFIs between patients with haematologic malignancy receiving… read more here.
Keywords: patients haematologic; haematologic malignancy; oral suspension; antifungal prophylaxis ... See more keywords
Using State Transition Models To Explore How the Prevalence of Subtherapeutic Posaconazole Exposures Impacts the Clinical Utility of Therapeutic Drug Monitoring for Posaconazole Tablets and Oral Suspension
Sign Up to like & getrecommendations! Published in 2019 at "Antimicrobial Agents and Chemotherapy"
DOI: 10.1128/aac.01435-19
Abstract: Therapeutic drug monitoring (TDM) has been recommended in guidelines for patients receiving posaconazole oral suspension, but its utility in patients receiving posaconazole tablet, which has an improved bioavailability, remains unclear. ABSTRACT Therapeutic drug monitoring (TDM)… read more here.
Keywords: model; suspension; therapeutic drug; utility ... See more keywords
Quantitative Analysis of Abamectin, Albendazole, Levamisole HCl and Closantel in Q-DRENCH Oral Suspension Using a Stability-Indicating HPLC-DAD Method
Sign Up to like & getrecommendations! Published in 2022 at "Molecules"
DOI: 10.3390/molecules27030764
Abstract: Combination therapy of many anthelmintic drugs has been used to achieve fast animal curing. Q-DRENCH is an oral suspension, containing four different active drugs against GIT worms in sheep, commonly used in Australia and New… read more here.
Keywords: analysis; levamisole hcl; method; oral suspension ... See more keywords
Performance equivalence and validation of a rapid microbiological method for detection and quantification of yeast and mold in an antacid oral suspension.
Sign Up to like & getrecommendations! Published in 2023 at "PDA journal of pharmaceutical science and technology"
DOI: 10.5731/pdajpst.2021.012632
Abstract: Alternative and rapid microbiological methods are effective and profitable technologies that can be safely use in the pharmaceutical industry. This report studies the efficacy of the Soleris® direct yeast and mold automated method for the… read more here.
Keywords: validation; antacid oral; detection; yeast mold ... See more keywords