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   Articles with "oral tolerance" as a keyword



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Role of the Microbiome in Food Allergy

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recommendations! Published in 2018 at "Current Allergy and Asthma Reports"

DOI: 10.1007/s11882-018-0780-z

Abstract: Purpose of ReviewResident microbial communities likely modify risk for allergic disorders, including food allergy. We review epidemiologic studies linking microbial exposures to food allergy risk and discuss the mechanisms by which the microbiome may modulate… read more here.

Keywords: food allergy; oral tolerance; microbiome food; food ... See more keywords

Oral tolerance and the materno-fetal relationship.

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recommendations! Published in 2019 at "Journal of reproductive immunology"

DOI: 10.1016/j.jri.2019.07.003

Abstract: Oral administration of antigen is a potent route for induction of systemic tolerance. Regulatory T cells and TH3 cellsare generated at intestinal mucosal sites. Oral exposure to antigens in seminal plasma has been suggested to… read more here.

Keywords: tolerance materno; tolerance; materno fetal; oral tolerance ... See more keywords

Recombinant allergen and peptide-based approaches for allergy prevention by oral tolerance.

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recommendations! Published in 2017 at "Seminars in immunology"

DOI: 10.1016/j.smim.2017.08.017

Abstract: Several studies conducted in animal models for immunologically-mediated hypersensitivity diseases have shown that oral administration of antigens early in life can prevent the development of specific humoral and cellular immune responses and thus hypersensitivity reactions… read more here.

Keywords: tolerance; allergen peptide; recombinant allergen; oral tolerance ... See more keywords
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Regulatory T Cells in Bioactive Peptides-Induced Oral Tolerance; a Two-Edged Sword Related to the Risk of Chronic Diseases: A Systematic Review

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recommendations! Published in 2020 at "Nutrition and Cancer"

DOI: 10.1080/01635581.2020.1784442

Abstract: Abstract This systematic review assesses the literature regarding beneficial and potential detrimental effects of bioactive peptides (BPs), focusing on evidence of regulatory T cells (T-regs) mediated oral tolerance (OT), collagen hydrolysate (CH) supplementation in osteoarthritis… read more here.

Keywords: risk; systematic review; regulatory cells; oral tolerance ... See more keywords

Pyruvate enhances oral tolerance via GPR31.

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recommendations! Published in 2022 at "International immunology"

DOI: 10.1093/intimm/dxac010

Abstract: CX3CR1 high myeloid cells in the small intestine mediate the induction of oral tolerance by driving regulatory T (Treg) cells. Bacterial metabolites, e.g., pyruvate and lactate, induce a dendrite extension of CX3CR1 high myeloid cells… read more here.

Keywords: oral tolerance; tolerance; pyruvate; mice ... See more keywords
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Pediatric Allergic Diseases, Food Allergy, and Oral Tolerance.

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recommendations! Published in 2020 at "Annual review of cell and developmental biology"

DOI: 10.1146/annurev-cellbio-100818-125346

Abstract: Pediatric allergic disease is a significant health concern worldwide, and the prevalence of childhood eczema, asthma, allergic rhinitis, and food allergy continues to increase. Evidence to support specific interventions for the prevention of eczema, asthma,… read more here.

Keywords: food allergy; pediatric allergic; oral tolerance; biology ... See more keywords

Evaluating the Effects of Chronic Oral Exposure to the Food Additive Silicon Dioxide on Oral Tolerance Induction and Food Sensitivities in Mice

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recommendations! Published in 2024 at "Environmental Health Perspectives"

DOI: 10.1289/ehp12758

Abstract: Background: The increasing prevalence of food sensitivities has been attributed to changes in gut microenvironment; however, ubiquitous environmental triggers such as inorganic nanoparticles (NPs) used as food additives have not been thoroughly investigated. Objectives: We… read more here.

Keywords: mice; food; food sensitivities; oral tolerance ... See more keywords

Oral tolerance:Recent advances on mechanisms and potential applications.

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recommendations! Published in 2018 at "Asian Pacific journal of allergy and immunology"

DOI: 10.12932/ap0848

Abstract: Oral tolerance is a type of immune hypo-responsiveness induced by oral administration of food or harmless gastrointestinal antigens. It is evident that the induction of oral tolerance can protect our body from enteric problems, such… read more here.

Keywords: tolerance recent; tolerance; oral tolerance; applications oral ... See more keywords

Ingestion of egg white after acquisition of oral tolerance with heated egg white in OVA-sensitized mice caused severe allergic symptoms

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recommendations! Published in 2025 at "Bioscience of Microbiota, Food and Health"

DOI: 10.12938/bmfh.2024-126

Abstract: Heated eggs have often been used for oral immunotherapy of egg allergy because of their lower allergenicity than raw eggs. Furthermore, recent guidelines recommend the earlier introduction of well-cooked eggs to the diet as a… read more here.

Keywords: oral tolerance; egg white; ova sensitized; allergic symptoms ... See more keywords

Systemic effects of oral tolerance improve the healing of several and concomitant wounds on different parts of the body

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recommendations! Published in 2025 at "Brazilian Journal of Medical and Biological Research"

DOI: 10.1590/1414-431x2025e14689

Abstract: Oral tolerance is an immunological phenomenon that results from protein intake and that has systemic effects on inflammation. Previous research has shown that parenteral injection of tolerated proteins reduces inflammatory infiltrate and improves skin wound… read more here.

Keywords: oral tolerance; tolerance; systemic effects; healing several ... See more keywords

Breast milk microRNAs: Potential players in oral tolerance development

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recommendations! Published in 2023 at "Frontiers in Immunology"

DOI: 10.3389/fimmu.2023.1154211

Abstract: Breast milk is an essential source of nutrition and hydration for the infant. In addition, this highly complex biological fluid contains numerous immunologically active factors such as microorganisms, immunoglobulins, cytokines and microRNAs (miRNAs). Here, we… read more here.

Keywords: breast milk; oral tolerance; milk; tolerance development ... See more keywords