Articles with "oral tolerance" as a keyword



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Role of the Microbiome in Food Allergy

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Published in 2018 at "Current Allergy and Asthma Reports"

DOI: 10.1007/s11882-018-0780-z

Abstract: Purpose of ReviewResident microbial communities likely modify risk for allergic disorders, including food allergy. We review epidemiologic studies linking microbial exposures to food allergy risk and discuss the mechanisms by which the microbiome may modulate… read more here.

Keywords: food allergy; oral tolerance; microbiome food; food ... See more keywords
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Oral tolerance and the materno-fetal relationship.

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Published in 2019 at "Journal of reproductive immunology"

DOI: 10.1016/j.jri.2019.07.003

Abstract: Oral administration of antigen is a potent route for induction of systemic tolerance. Regulatory T cells and TH3 cellsare generated at intestinal mucosal sites. Oral exposure to antigens in seminal plasma has been suggested to… read more here.

Keywords: tolerance materno; tolerance; materno fetal; oral tolerance ... See more keywords
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Recombinant allergen and peptide-based approaches for allergy prevention by oral tolerance.

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Published in 2017 at "Seminars in immunology"

DOI: 10.1016/j.smim.2017.08.017

Abstract: Several studies conducted in animal models for immunologically-mediated hypersensitivity diseases have shown that oral administration of antigens early in life can prevent the development of specific humoral and cellular immune responses and thus hypersensitivity reactions… read more here.

Keywords: tolerance; allergen peptide; recombinant allergen; oral tolerance ... See more keywords
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Regulatory T Cells in Bioactive Peptides-Induced Oral Tolerance; a Two-Edged Sword Related to the Risk of Chronic Diseases: A Systematic Review

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Published in 2020 at "Nutrition and Cancer"

DOI: 10.1080/01635581.2020.1784442

Abstract: Abstract This systematic review assesses the literature regarding beneficial and potential detrimental effects of bioactive peptides (BPs), focusing on evidence of regulatory T cells (T-regs) mediated oral tolerance (OT), collagen hydrolysate (CH) supplementation in osteoarthritis… read more here.

Keywords: risk; systematic review; regulatory cells; oral tolerance ... See more keywords
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Pyruvate enhances oral tolerance via GPR31.

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Published in 2022 at "International immunology"

DOI: 10.1093/intimm/dxac010

Abstract: CX3CR1 high myeloid cells in the small intestine mediate the induction of oral tolerance by driving regulatory T (Treg) cells. Bacterial metabolites, e.g., pyruvate and lactate, induce a dendrite extension of CX3CR1 high myeloid cells… read more here.

Keywords: oral tolerance; tolerance; pyruvate; mice ... See more keywords
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Pediatric Allergic Diseases, Food Allergy, and Oral Tolerance.

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Published in 2020 at "Annual review of cell and developmental biology"

DOI: 10.1146/annurev-cellbio-100818-125346

Abstract: Pediatric allergic disease is a significant health concern worldwide, and the prevalence of childhood eczema, asthma, allergic rhinitis, and food allergy continues to increase. Evidence to support specific interventions for the prevention of eczema, asthma,… read more here.

Keywords: food allergy; pediatric allergic; oral tolerance; biology ... See more keywords
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Oral tolerance:Recent advances on mechanisms and potential applications.

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Published in 2018 at "Asian Pacific journal of allergy and immunology"

DOI: 10.12932/ap0848

Abstract: Oral tolerance is a type of immune hypo-responsiveness induced by oral administration of food or harmless gastrointestinal antigens. It is evident that the induction of oral tolerance can protect our body from enteric problems, such… read more here.

Keywords: tolerance recent; tolerance; oral tolerance; applications oral ... See more keywords
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Breast milk microRNAs: Potential players in oral tolerance development

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Published in 2023 at "Frontiers in Immunology"

DOI: 10.3389/fimmu.2023.1154211

Abstract: Breast milk is an essential source of nutrition and hydration for the infant. In addition, this highly complex biological fluid contains numerous immunologically active factors such as microorganisms, immunoglobulins, cytokines and microRNAs (miRNAs). Here, we… read more here.

Keywords: breast milk; oral tolerance; milk; tolerance development ... See more keywords
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Characteristics of Exogenous Allergen in Breast Milk and Their Impact on Oral Tolerance Induction

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Published in 2022 at "Frontiers in Pediatrics"

DOI: 10.3389/fped.2022.830718

Abstract: Food allergy is a common health problem in childhood since its prevalence was estimated to range from 6. 5 to 24.6% in European countries. Recently, a lot of research has focused on the impact of… read more here.

Keywords: allergen; tolerance induction; oral tolerance; milk ... See more keywords
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Hypoallergenic Wheat Line (1BS-18H) Lacking ω5-Gliadin Induces Oral Tolerance to Wheat Gluten Proteins in a Rat Model of Wheat Allergy

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Published in 2022 at "Foods"

DOI: 10.3390/foods11152181

Abstract: The early ingestion of food can prevent the onset of food allergy related to inducing oral tolerance (OT). We developed the Hokushin wheat line as a hypoallergenic wheat (1BS-18H) lacking ω5-gliadin, a major allergen of… read more here.

Keywords: oral tolerance; wheat line; wheat; wheat allergy ... See more keywords
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Oral Tolerance Induction—Opportunities and Mechanisms

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Published in 2022 at "Foods"

DOI: 10.3390/foods11213386

Abstract: Oral tolerance is the active absence of response to food allergens, which involves complex mechanisms in the gut-associated lymphoid tissue. Food allergy results from the disruption of such tolerance or the absence of its establishment… read more here.

Keywords: tolerance induction; tolerance; oral tolerance; food allergy ... See more keywords