Biodegradable polymers in drug delivery and oral vaccination
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DOI: 10.1016/j.eurpolymj.2020.110155
Abstract: Abstract Over the years biodegradable polymers have emerged as promising polymeric materials in drug delivery and vaccination due to their fascinating properties like biocompatibility, biodegradability, and minimal toxicity. Poor bioavailability is still the major issue… read more here.
Keywords: drug delivery; delivery; biodegradable polymers; oral vaccination ... See more keywords
Efficient oral vaccination by bioengineering virus-like particles with protozoan surface proteins
Sign Up to like & getrecommendations! Published in 2019 at "Nature Communications"
DOI: 10.1038/s41467-018-08265-9
Abstract: Intestinal and free-living protozoa, such as Giardia lamblia, express a dense coat of variant-specific surface proteins (VSPs) on trophozoites that protects the parasite inside the host’s intestine. Here we show that VSPs not only are… read more here.
Keywords: surface proteins; virus like; surface; efficient oral ... See more keywords
Primary oral vaccination followed by a vaginal pull protects mice against genital HSV‐2 infection
Sign Up to like & getrecommendations! Published in 2022 at "American Journal of Reproductive Immunology"
DOI: 10.1111/aji.13668
Abstract: HSV‐2 infected more than 491 million people aged 15–49 world‐wide in 2016. The morbidity associated with recurrent infections and the increased risk of HIV infection make this a major health problem. To date there is… read more here.
Keywords: primary oral; followed vaginal; infection; oral vaccination ... See more keywords
Oral Vaccination Approaches for Anti-SHIV Immunity
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DOI: 10.3389/fimmu.2021.702705
Abstract: We modified a Sabin Oral Poliovirus Vaccine (OPV) vector to permit secretion of the antigens of interest with the goal of improving anti-HIV Env humoral responses in a SHIV mucosal immunization composed of DNA and… read more here.
Keywords: immunity; cell mediated; oral vaccination; vaccination approaches ... See more keywords
Oral vaccination of fish against vibriosis using spore-display technology
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.1012301
Abstract: Oral vaccines are highly demanded by the aquaculture sector, to allow mass delivery of antigens without using the expensive and labor-intensive injectable vaccines. These later require individual handling of fish, provoking stress-related mortalities. One possible… read more here.
Keywords: technology; vaccination fish; display; carrying spores ... See more keywords