Articles with "oral vancomycin" as a keyword



Oral Vancomycin for Prevention of Recurrent Clostridioides difficile Infection

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Published in 2025 at "JAMA Network Open"

DOI: 10.1001/jamanetworkopen.2025.17834

Abstract: This randomized clinical trial examines whether prophylactic oral vancomycin vs placebo reduces recurrent Clostridioides difficile infection in adults receiving antibiotics for another indication. read more here.

Keywords: clostridioides difficile; recurrent clostridioides; oral vancomycin; difficile infection ... See more keywords
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Successful response of primary sclerosing cholangitis and associated ulcerative colitis to oral vancomycin may depend on brand and personalized dose: report in an adolescent

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Published in 2020 at "Clinical Journal of Gastroenterology"

DOI: 10.1007/s12328-020-01296-0

Abstract: Primary sclerosing cholangitis (PSC) is a rare, progressive liver disease characterized by cholestasis and bile duct fibrosis that has no accepted therapy known to delay or arrest its progression. We report a 23-year-old female patient… read more here.

Keywords: vancomycin; primary sclerosing; ulcerative colitis; oral vancomycin ... See more keywords
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Effect of oral vancomycin dose on outcomes in patients with Clostridioides difficile infection.

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Published in 2021 at "International journal of antimicrobial agents"

DOI: 10.1016/j.ijantimicag.2021.106311

Abstract: BACKGROUND Clostridioides difficile infection (CDI) is a significant cause of morbidity and mortality. Oral vancomycin is a cornerstone of CDI treatment, but dosing strategies in clinical practice may differ from guideline recommendations. The purpose of… read more here.

Keywords: vancomycin; difficile infection; high dose; clostridioides difficile ... See more keywords

Oral Vancomycin Followed by Fecal Transplantation Versus Tapering Oral Vancomycin Treatment for Recurrent Clostridium difficile Infection: An Open-Label, Randomized Controlled Trial

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Published in 2017 at "Clinical Infectious Diseases"

DOI: 10.1093/cid/ciw731

Abstract: Background. Fecal transplantation (FT) is a promising treatment for recurrent Clostridium difficile infection (CDI), but its true effectiveness remains unknown. We compared 14 days of oral vancomycin followed by a single FT by enema with… read more here.

Keywords: vancomycin; cdi; fecal transplantation; treatment ... See more keywords

Oral Vancomycin Induced and Maintained Clinical and Endoscopic Remission in Ulcerative Colitis and Primary Sclerosing Cholangitis Post-liver Transplantation.

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Published in 2023 at "Inflammatory bowel diseases"

DOI: 10.1093/ibd/izad040

Abstract: We present a case of a 34-year-old man with primary sclerosing cholangitis and associated ulcerative colitis refractory to multiple advanced therapies who achieved clinical and endoscopic remission with oral vancomycin therapy. read more here.

Keywords: endoscopic remission; oral vancomycin; sclerosing cholangitis; primary sclerosing ... See more keywords
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88. Impact of a Computerized Clinical Decision Support Tool on clostridioides Difficile Testing and Oral Vancomycin Utilization as a Balancing Metric

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Published in 2020 at "Open Forum Infectious Diseases"

DOI: 10.1093/ofid/ofaa439.398

Abstract: Over diagnosis of hospital-onset Clostridioides difficile infection (HO-CDI) is directly tied to inappropriate C. difficile testing which does not distinguish between infected or colonized individuals. This can lead to inappropriate therapy. Multiple studies have utilized… read more here.

Keywords: utilization balancing; difficile testing; vancomycin utilization; oral vancomycin ... See more keywords
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Randomized Controlled Trial of Oral Vancomycin Treatment in Clostridioides difficile-Colonized Patients

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Published in 2021 at "mSphere"

DOI: 10.1128/msphere.00936-20

Abstract: A gold standard diagnostic for Clostridioides difficile infection (CDI) does not exist. An area of controversy is how to manage patients whose stool tests positive by nucleic acid amplification tests but negative by toxin enzyme… read more here.

Keywords: oral vancomycin; vancomycin; treatment; clostridioides difficile ... See more keywords

Oral vancomycin is associated with less therapy intensification in adults with symptomatic inflammatory bowel disease and underlying primary sclerosing cholangitis

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Published in 2025 at "Annals of Gastroenterology"

DOI: 10.20524/aog.2025.0978

Abstract: Background Case reports describe the use of oral vancomycin therapy (OVT) in adult patients with concomitant symptomatic inflammatory bowel disease (IBD) and primary sclerosing cholangitis (PSC). OVT is associated with a higher likelihood of IBD… read more here.

Keywords: disease; oral vancomycin; intensification; therapy intensification ... See more keywords

Effective Dosage of Oral Vancomycin in Treatment for Initial Episode of Clostridioides difficile Infection: A Systematic Review and Meta-Analysis

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Published in 2019 at "Antibiotics"

DOI: 10.3390/antibiotics8040173

Abstract: Background: Oral vancomycin is a first line treatment for an initial episode of Clostridioides difficile infection. However, the comparative efficacy of different dosing regimens is lacking evidence in the current literature. Methods: We searched PubMed,… read more here.

Keywords: difficile infection; clostridioides difficile; treatment initial; oral vancomycin ... See more keywords

Hepatic Histopathological Benefit, Microbial Cost: Oral Vancomycin Mitigates Non-Alcoholic Fatty Liver Disease While Disrupting the Cecal Microbiota

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Published in 2025 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms26178616

Abstract: Non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH) encompasses a spectrum of liver conditions and involves gut–liver axis crosstalk. We aimed to evaluate whether oral vancomycin modifies liver injury and the cecal microbiota in… read more here.

Keywords: oral vancomycin; mcd; microbiota; cecal microbiota ... See more keywords