MCM2-7 loading-dependent ORC release ensures genome-wide origin licensing
Sign Up to like & getrecommendations! Published in 2024 at "Nature Communications"
DOI: 10.1038/s41467-024-51538-9
Abstract: Origin recognition complex (ORC)-dependent loading of the replicative helicase MCM2-7 onto replication origins in G1-phase forms the basis of replication fork establishment in S-phase. However, how ORC and MCM2-7 facilitate genome-wide DNA licensing is not… read more here.
Keywords: genome wide; orc release; origin licensing; orc ... See more keywords