Network-based prediction of drug-target interactions using an arbitrary-order proximity embedded deep forest
Sign Up to like & getrecommendations! Published in 2020 at "Bioinformatics"
DOI: 10.1093/bioinformatics/btaa010
Abstract: MOTIVATION Systematic identification of molecular targets among known drugs plays an essential role in drug repurposing and understanding of their unexpected side effects. Computational approaches for prediction of drug-target interactions (DTIs) are highly desired in… read more here.
Keywords: network based; network; deep forest; drug ... See more keywords
hpGAT: High-Order Proximity Informed Graph Attention Network
Sign Up to like & getrecommendations! Published in 2019 at "IEEE Access"
DOI: 10.1109/access.2019.2938039
Abstract: Graph neural networks (GNNs) have recently made remarkable breakthroughs in the paradigm of learning with graph-structured data. However, most existing GNNs limit the receptive field of the node on each layer to its connected (one-hop)… read more here.
Keywords: order proximity; graph attention; high order;