Sleep/wake disorders and the hypocretin/orexin system in a zebrafish model of Parkinson’s Disease
Sign Up to like & getrecommendations! Published in 2017 at "Mechanisms of Development"
DOI: 10.1016/j.mod.2017.04.352
Abstract: ICM P09-015-F FONDECYT 3150540 1161274 1151029 CONICYT PIA ACT1402 FONDAP 15150012 read more here.
Keywords: sleep wake; hypocretin orexin; system zebrafish; disorders hypocretin ... See more keywords
The Insomnia-Addiction Positive Feedback Loop: Role of the Orexin System
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers of neurology and neuroscience"
DOI: 10.1159/000514965
Abstract: Significant sleep impairments often accompany substance use disorders (SUDs). Sleep disturbances in SUD patients are associated with poor clinical outcomes and treatment adherence, emphasizing the importance of normalizing sleep when treating SUDs. Orexins (hypocretins) are… read more here.
Keywords: addiction; orexin; role orexin; orexin system ... See more keywords
Abstract MP06: Kinin B1 Receptor Mediates Orexin System Hyperactivity In Salt-sensitive Hypertension
Sign Up to like & getrecommendations! Published in 2020 at "Hypertension"
DOI: 10.1161/hyp.76.suppl_1.mp06
Abstract: Hyperactivity of the orexin system contributes to several animal models of hypertension and enhances arginine vasopressin (AVP) release. We previously reported higher neuronal kinin B1 receptor (B1... read more here.
Keywords: hyperactivity; kinin receptor; orexin system; hypertension ... See more keywords
Characteristics of Seltorexant—Innovative Agent Targeting Orexin System for the Treatment of Depression and Anxiety
Sign Up to like & getrecommendations! Published in 2023 at "Molecules"
DOI: 10.3390/molecules28083575
Abstract: Twenty-five years have passed since the discovery of the orexin system, during which time we have learned more and more about it. A number of studies have been conducted showing the role of the orexin… read more here.
Keywords: treatment depression; orexin system; orexin;