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Published in 2018 at "Acupuncture in Medicine"
DOI: 10.1136/acupmed-2017-011391
Abstract: Objectives Decreased lung function in chronic obstructive pulmonary disease (COPD) is correlated with abnormal excitability of the respiratory centre where orexin neuropeptides from the hypothalamus are responsible for regulating respiration. We hypothesised that improvements in…
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Keywords:
orexin;
orexins receptors;
copd;
model ... See more keywords
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Published in 2022 at "Frontiers in Endocrinology"
DOI: 10.3389/fendo.2022.931970
Abstract: At the end of the 20th century, two new neuropeptides (Orexin-A/hypocretin-1 and Orexin-B/hypocretins-2) expressed in hypothalamus as a prepro-orexins precursor, were discovered. These two neuropeptides interacted with two G protein-coupled receptor isoforms named OX1R and…
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Keywords:
anti tumoral;
orexins receptors;
tumoral properties;
receptors structural ... See more keywords