SARS-CoV-2 accessory proteins ORF7a and ORF3a use distinct mechanisms to down-regulate MHC-I surface expression
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DOI: 10.1073/pnas.2208525120
Abstract: Significance Viruses may downregulate MHC class I expression on infected cells to avoid elimination by cytotoxic T cells. We report that the accessory proteins ORF7a and ORF3a of SARS-CoV-2 mediate this function and delineate the… read more here.
Keywords: expression; orf7a orf3a; distinct mechanisms; accessory proteins ... See more keywords