High Burden of Subclinical Cardiovascular Target Organ Damage After Pediatric Liver Transplantation
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DOI: 10.1002/lt.25431
Abstract: Cardiovascular (CV) events account for 8%‐13% of deaths after liver transplantation (LT) in adulthood. Although CV risk factors (RFs) are present, little is known about the prevalence of subclinical CV target organ damage (TOD) in… read more here.
Keywords: burden subclinical; target organ; organ damage; transplantation ... See more keywords
The titers of antinuclear antibodies are associated with the degree of inflammation and organ damage in Primary Sjögren's Syndrome
Sign Up to like & getrecommendations! Published in 2024 at "Clinical and Experimental Medicine"
DOI: 10.1007/s10238-024-01357-5
Abstract: Primary Sjögren’s Syndrome (pSS) falls within the category of connective tissue diseases, characterized by the presence of autoantibodies such as antinuclear antibodies (ANA). However, according to the classification criteria for pSS, some patients may exhibit… read more here.
Keywords: damage; primary gren; antinuclear antibodies; organ damage ... See more keywords
Is high IgG level associated with disease activity and organ damage in patients with Sjögren’s syndrome? A 3-year follow-up cohort study
Sign Up to like & getrecommendations! Published in 2025 at "Clinical and Experimental Medicine"
DOI: 10.1007/s10238-025-01715-x
Abstract: Hypergammaglobulinemia is prevalent in primary Sjögren’s syndrome (pSS) and is considered a marker of disease activity. However, limited data exist regarding its association with disease activity and organ damage. We enrolled patients with pSS from… read more here.
Keywords: igg; disease activity; organ damage;
Effect of diosmin on lipid peoxidation and organ damage against subacute deltamethrin exposure in rats
Sign Up to like & getrecommendations! Published in 2020 at "Environmental Science and Pollution Research"
DOI: 10.1007/s11356-020-11277-y
Abstract: The aim of this study was to investigate the protective efficacy of diosmin against subacute deltamethrin exposure. For this purpose, 40 male Wistar albino rats were used. The animals were assigned to the following 4… read more here.
Keywords: deltamethrin; group; organ damage; deltamethrin exposure ... See more keywords
Effect of a normal protein diet on oxidative stress and organ damage in malnourished rats
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DOI: 10.1007/s11515-018-1511-5
Abstract: BackgroundWe investigated the effects of three weeks of renutrition with a normal protein diet on oxidant/antioxidant status in malnourished rats using biochemistry and histology.MethodsEighteen young Wistar rats were divided into three groups: control group was… read more here.
Keywords: protein; normal protein; malnourished rats; organ damage ... See more keywords
Smoking and pre-existing organ damage reduce the efficacy of belimumab in systemic lupus erythematosus.
Sign Up to like & getrecommendations! Published in 2017 at "Autoimmunity reviews"
DOI: 10.1016/j.autrev.2017.02.005
Abstract: OBJECTIVES Belimumab is the first biologic drug approved for Systemic Lupus Erythematosus (SLE). Here, we aimed to investigate the effects of belimumab on clinical and serologic outcomes, and sought to identify predictors of treatment response… read more here.
Keywords: systemic lupus; organ damage; lupus erythematosus; damage ... See more keywords
Tissue resident cell processes determine organ damage in systemic lupus erythematosus.
Sign Up to like & getrecommendations! Published in 2021 at "Clinical immunology"
DOI: 10.1016/j.clim.2021.108919
Abstract: Systemic lupus erythematosus (SLE) is an autoimmune disease that affects almost any organ. Multiple immunological abnormalities involving every domain of the immune system contribute to the expression of the disease. It is now recognized that… read more here.
Keywords: damage; systemic lupus; tissue resident; lupus erythematosus ... See more keywords
MicroRNA‐146a protects against LPS‐induced organ damage by inhibiting Notch1 in macrophage
Sign Up to like & getrecommendations! Published in 2018 at "International Immunopharmacology"
DOI: 10.1016/j.intimp.2018.07.040
Abstract: &NA; MicroRNA‐146a is a well‐studied microRNA participating in immune and inflammatory diseases, but its role in sepsis has not been investigated. Here in our study, we found increased level of microRNA‐146a in macrophage stimulated by… read more here.
Keywords: notch1 macrophage; mir 146a; organ damage; microrna 146a ... See more keywords
Enzymatic Synthesis of Chondroitin Sulfate E to Attenuate Bacteria Lipopolysaccharide-Induced Organ Damage
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DOI: 10.1021/acscentsci.0c00712
Abstract: Chondroitin sulfate E (CS-E) is a sulfated polysaccharide that contains repeating disaccharides of 4,6-disulfated N-acetylgalactosamine and glucuronic acid residues. Here, we report the enzymatic synthesis of three homogeneous CS-E oligosaccharides, including CS-E heptasaccharide (CS-E 7-mer),… read more here.
Keywords: mer; enzymatic synthesis; chondroitin sulfate; organ damage ... See more keywords
Serum-soluble (pro)renin receptor concentration as a biomarker for organ damage in primary aldosteronism
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DOI: 10.1038/s41440-019-0312-9
Abstract: Primary aldosteronism is characterized by inappropriate overproduction of aldosterone by adrenal lesions and leads to hypertension. Excess aldosterone causes organ damage; therefore, finding a biomarker for organ damage risk is vital. The (pro)renin receptor regulates… read more here.
Keywords: renin; renin receptor; organ damage; pro renin ... See more keywords
Left atrial volume indexed for height2 is a new sensitive marker for subclinical cardiac organ damage in female hypertensive patients
Sign Up to like & getrecommendations! Published in 2021 at "Hypertension Research"
DOI: 10.1038/s41440-021-00614-4
Abstract: Left atrial enlargement (LAe) is a subclinical marker of hypertensive-mediated organ damage, which is important to identify in cardiovascular risk stratification. Recently, LA indexing for height was suggested as a more accurate marker of defining… read more here.
Keywords: organ damage; atrial volume; hypertensive patients; marker ... See more keywords