Systems biology of the IMIDIA biobank from organ donors and pancreatectomised patients defines a novel transcriptomic signature of islets from individuals with type 2 diabetes
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DOI: 10.1007/s00125-017-4500-3
Abstract: Aims/hypothesisPancreatic islet beta cell failure causes type 2 diabetes in humans. To identify transcriptomic changes in type 2 diabetic islets, the Innovative Medicines Initiative for Diabetes: Improving beta-cell function and identification of diagnostic biomarkers for… read more here.
Keywords: organ donors; type diabetic; type diabetes; biology ... See more keywords
Anesthesia Management of Organ Donors.
Sign Up to like & getrecommendations! Published in 2017 at "Anesthesiology clinics"
DOI: 10.1016/j.anclin.2017.04.003
Abstract: The shortage of suitable organs is the biggest obstacle for transplants. At present, most organs for transplant in the United States are from donation after neurologic determination of death (brain death). Potential organs for transplant… read more here.
Keywords: anesthesia management; death; organ donors; management ... See more keywords
Lack of Impact of Hyperchloremia in Brain-Dead Organ Donors on the Onset of Kidney Allograft Function in the Recipients.
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DOI: 10.1016/j.transproceed.2017.02.053
Abstract: BACKGROUND Hyperchloremia produces renal vasoconstriction and fall in glomerular filtration rate. In 90% of brain-dead organ donors, diabetes insipidus develops, characterized by inappropriate diuresis, hyperosmolality, and hyperchloremia. The aim of this study was to determine… read more here.
Keywords: function; organ donors; hyperchloremia; kidney allograft ... See more keywords
Effect of a multidisciplinary program to improve organ donation in the emergency department.
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DOI: 10.1097/mej.0000000000000752
Abstract: BACKGROUND AND IMPORTANCE As the emergency department (ED) is an important source of potential organ donors, it may play an important role in the organ donation process. OBJECTIVE To assess the effectiveness of the multidisciplinary… read more here.
Keywords: deceased organ; emergency; organ donors; donation ... See more keywords
Deceased Organ Donors and PHS Risk Identification: Impact on Organ Usage and Outcomes
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DOI: 10.1097/tp.0000000000001716
Abstract: Background In 2013, the public health service (PHS) changed the criteria intended to identify organ donors that put the associated organ recipients at increased risk for acquiring human immunodeficiency virus (HIV), hepatitis B virus (HBV),… read more here.
Keywords: risk; phs donor; organ donors; hcv ... See more keywords
Early Assessment of National Kidney Allocation Policy Change.
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DOI: 10.1097/xcs.0000000000000096
Abstract: BACKGROUND The new kidney allocation changes with elimination of donor service areas (DSAs) and Organ Procurement and Transplantation Network regions were initiated to improve equity in organ allocation. The aim of this evaluation was to… read more here.
Keywords: kidney; allocation; organ donors; allocation policy ... See more keywords
Kidney nonprocurement in solid organ donors in the United States
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DOI: 10.1111/ajt.15952
Abstract: There are limited data on the nonprocurement of kidneys from solid organ donors. Analysis of Standard Transplant Analysis and Research files was undertaken on all deceased donors in the United States with at least 1… read more here.
Keywords: solid organ; kidney nonprocurement; organ donors; donors united ... See more keywords
Use of SARS‐CoV‐2 infected deceased organ donors: Should we always “just say no?”
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DOI: 10.1111/ajt.16000
Abstract: In the context of a rapidly evolving pandemic, multiple organizations have released guidelines stating that all organs from potential deceased donors with severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) infection should be deferred, including from… read more here.
Keywords: cov infected; infected deceased; organ donors; use sars ... See more keywords
Potential organ donors with primary brain tumours: missed opportunities for donation and transplantation identified in Australian cohort study 2010–2015
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DOI: 10.1111/ans.18037
Abstract: Potential organ donors with primary brain tumours (PBT) frequently donate, however some may be declined due to uncertainty about tumour classification or transmission risk to transplant recipients. We sought to describe transmission risk and donation… read more here.
Keywords: missed opportunities; potential organ; brain tumours; primary brain ... See more keywords
The benefits of initiating continuous renal replacement therapy after brain death in organ donors with oligoanuric acute kidney injury
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DOI: 10.1111/ctr.14764
Abstract: Acute kidney injury (AKI) in deceased organ donors is increasing due to the escalation in anoxic brain‐deaths. The management of an organ donor with oligoanuric AKI is frequently curtailed due to hemodynamic and electrolyte instability.… read more here.
Keywords: donors oligoanuric; acute kidney; brain; oligoanuric aki ... See more keywords
Infections and associated behaviors among deceased organ donors: Informing the assessment of risk
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DOI: 10.1111/tid.13055
Abstract: For infectious disease risk assessment among deceased organ donors, pre‐donation clinical, microbiological, and behavioral information are reviewed; however, uncertainty may arise due to false negative screening results of recently acquired infections. read more here.
Keywords: risk; organ donors; deceased organ; among deceased ... See more keywords