Complement as driver of systemic inflammation and organ failure in trauma, burn, and sepsis
Sign Up to like & getrecommendations! Published in 2021 at "Seminars in Immunopathology"
DOI: 10.1007/s00281-021-00872-x
Abstract: Complement is one of the most ancient defense systems. It gets strongly activated immediately after acute injuries like trauma, burn, or sepsis and helps to initiate regeneration. However, uncontrolled complement activation contributes to disease progression… read more here.
Keywords: trauma burn; complement; organ failure; burn sepsis ... See more keywords
Heparin-Binding Protein Levels at Admission and Within 24 h Are Associated with Persistent Organ Failure in Acute Pancreatitis
Sign Up to like & getrecommendations! Published in 2020 at "Digestive Diseases and Sciences"
DOI: 10.1007/s10620-020-06660-1
Abstract: Background Identification of patients at risk for persistent organ failure (POF) early in the course of acute pancreatitis (AP) is critical for early intervention. Heparin-binding protein (HBP) levels are closely related to inflammation. Therefore, we… read more here.
Keywords: acute pancreatitis; organ failure; heparin binding; hbp ... See more keywords
Prehospital quick sequential organ failure assessment as a tool to predict in‐hospital mortality
Sign Up to like & getrecommendations! Published in 2018 at "American Journal of Emergency Medicine"
DOI: 10.1016/j.ajem.2018.02.009
Abstract: Objective This study aimed to evaluate the predictive ability of quick sequential organ failure assessment (qSOFA) score for in‐hospital mortality among patients transported by physician‐staffed helicopters. Methods We conducted a single‐center, retrospective observational study using… read more here.
Keywords: organ failure; hospital mortality; qsofa; sequential organ ... See more keywords
[Multiple organ failure after spontaneous return of circulation in cardiac arrest in children].
Sign Up to like & getrecommendations! Published in 2017 at "Anales de pediatria"
DOI: 10.1016/j.anpedi.2016.06.010
Abstract: OBJECTIVE To assess the frequency of the multiple organ failure and the prognostic value of multiple organ failure scores in children who have recovered from an in-hospital cardiac arrest. PATIENTS AND METHODS A single centre,… read more here.
Keywords: cardiac arrest; organ failure; multiple organ; circulation ... See more keywords
Low serum selenium is associated with the severity of organ failure in critically ill children.
Sign Up to like & getrecommendations! Published in 2018 at "Clinical nutrition"
DOI: 10.1016/j.clnu.2017.06.014
Abstract: BACKGROUND & AIMS Low concentration of serum selenium is associated with the inflammatory response and multiple organ failure in adult ICU-patients. Critically ill children are less well characterized. In this study, serum selenium concentration and… read more here.
Keywords: low serum; organ failure; serum selenium; selenium ... See more keywords
Increased levels of plasma cytokines and correlations to organ failure and 30-day mortality in critically ill Covid-19 patients
Sign Up to like & getrecommendations! Published in 2021 at "Cytokine"
DOI: 10.1016/j.cyto.2020.155389
Abstract: Background The infection caused by SARS CoV-2 has been postulated to induce a cytokine storm syndrome that results in organ failure and even death in a considerable number of patients. However, the inflammatory response in… read more here.
Keywords: covid patients; organ failure; mortality; critically ill ... See more keywords
Evaluation of the BISAP scoring system in prognostication of acute pancreatitis - A prospective observational study.
Sign Up to like & getrecommendations! Published in 2018 at "International journal of surgery"
DOI: 10.1016/j.ijsu.2018.04.026
Abstract: INTRODUCTION Severe acute pancreatitis has a high mortality and its early identification is important for management and risk stratification. The bedside index for severity in acute pancreatitis (BISAP) is a simple scoring system done at… read more here.
Keywords: acute pancreatitis; bisap; pancreatitis; organ failure ... See more keywords
Comparison of the performance of SOFA, qSOFA and SIRS for predicting mortality and organ failure among sepsis patients admitted to the intensive care unit in a middle‐income country
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Critical Care"
DOI: 10.1016/j.jcrc.2017.10.023
Abstract: Introduction: The Sepsis‐3 definition provides a change of two or more scores from zero or a known baseline of the Sequential Organ Failure Assessment (SOFA) as criteria of sepsis. The aim of this study was… read more here.
Keywords: sepsis; organ failure; mortality organ; mortality ... See more keywords
Targeting RAGE to prevent SARS-CoV-2-mediated multiple organ failure: Hypotheses and perspectives
Sign Up to like & getrecommendations! Published in 2021 at "Life Sciences"
DOI: 10.1016/j.lfs.2021.119251
Abstract: A novel infectious disease (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), was detected in December 2019 and declared as a global pandemic by the World Health. Approximately 15% of patients with COVID-19… read more here.
Keywords: targeting rage; sars cov; organ failure; multiple organ ... See more keywords
Supportive therapy during COVID-19: The proposed mechanism of short-chain fatty acids to prevent cytokine storm and multi-organ failure
Sign Up to like & getrecommendations! Published in 2021 at "Medical Hypotheses"
DOI: 10.1016/j.mehy.2021.110661
Abstract: The world is currently facing the COVID-19 pandemic that is taking a heavy toll on several countries. While many infected patients have a good prognosis, in some cases the progression can be serious and even… read more here.
Keywords: organ failure; cytokine storm; short chain; storm multi ... See more keywords
Rationale for Adjunctive Therapies for Pediatric Sepsis Induced Multiple Organ Failure.
Sign Up to like & getrecommendations! Published in 2017 at "Pediatric clinics of North America"
DOI: 10.1016/j.pcl.2017.06.007
Abstract: Adjunctive therapies have been proposed for use in at least 5 inflammation pathobiology phenotypes in pediatric sepsis-induced multiple organ failure. This article discusses host-pathogen interaction prototypes to facilitate understanding of the rationale for personalized therapy… read more here.
Keywords: induced multiple; organ failure; adjunctive therapies; pediatric sepsis ... See more keywords