Strategies for organ preservation: Current prospective and challenges
Sign Up to like & getrecommendations! Published in 2023 at "Cell Biology International"
DOI: 10.1002/cbin.11984
Abstract: In current therapeutic approaches, transplantation of organs provides the best available treatment for a myriad of end‐stage organ failures. However, shortage of organ donors, lacunae in preservation methods, and lack of a suitable match are… read more here.
Keywords: current prospective; preservation current; organ preservation; strategies organ ... See more keywords
Organ preservation vs primary surgery in the management of T3 laryngeal and hypopharyngeal cancers
Sign Up to like & getrecommendations! Published in 2018 at "European Archives of Oto-Rhino-Laryngology"
DOI: 10.1007/s00405-018-5047-8
Abstract: ObjectiveThe main objective is to compare the oncologic outcomes of patients with T3 laryngeal cancers who underwent total laryngectomy or organ preservation protocol (OPP) as the initial plan of management.Materials and methodsThis is a retrospective… read more here.
Keywords: organ preservation; laryngeal hypopharyngeal; preservation; laryngectomy ... See more keywords
Organ preservation in bladder cancer: an opportunity for truly personalized treatment
Sign Up to like & getrecommendations! Published in 2019 at "Nature Reviews Urology"
DOI: 10.1038/s41585-019-0199-x
Abstract: Radical treatment of many solid tumours has moved from surgery to multimodal organ preservation strategies combining systemic and local treatments. Trimodality bladder-preserving treatment (TMT) comprises maximal transurethral resection of the bladder tumour followed by radiotherapy… read more here.
Keywords: bladder cancer; organ preservation; bladder; treatment ... See more keywords
Organ Preservation in MSS Rectal Cancer
Sign Up to like & getrecommendations! Published in 2023 at "Clinics in Colon and Rectal Surgery"
DOI: 10.1055/s-0043-1767710
Abstract: Abstract Rectal cancer is a heterogeneous disease with complex genetic and molecular subtypes. Emerging progress of neoadjuvant therapy has led to increased pathological and clinical complete response (cCR) rates for microsatellite stable (MSS) rectal cancer,… read more here.
Keywords: mss rectal; preservation mss; organ preservation; rectal cancer ... See more keywords
Coding the Dead: Cardiopulmonary Resuscitation for Organ Preservation.
Sign Up to like & getrecommendations! Published in 2023 at "AJOB empirical bioethics"
DOI: 10.1080/23294515.2023.2180106
Abstract: BACKGROUND There is lack of consensus in the bioethics literature regarding the use of cardiopulmonary resuscitation (CPR) for organ-preserving purposes. In this study, we assessed the perspectives of clinicians in critical care settings to better… read more here.
Keywords: cpr; cpr organ; organ preservation; status ... See more keywords
Advances in organ preservation for transplantation
Sign Up to like & getrecommendations! Published in 2017 at "ANZ Journal of Surgery"
DOI: 10.1111/ans.13713
Abstract: Organ transplantation provides the best available therapy for a myriad of medical conditions, including end‐stage renal disease, hepatic failure and type I diabetes mellitus. The current clinical reality is, however, that there is a significant… read more here.
Keywords: organ preservation; transplantation; preservation transplantation; advances organ ... See more keywords
Molecules, Machines, and the Perfusate Milieu: Organ Preservation and Emerging Concepts for Heart Transplant
Sign Up to like & getrecommendations! Published in 2022 at "Innovations: Technology and Techniques in Cardiothoracic and Vascular Surgery"
DOI: 10.1177/15569845221127305
Abstract: Heart transplant remains the most durable treatment for endstage congestive heart failure. Since the first successful human heart transplant performed by Barnard in 1967, advances in organ procurement, understanding of organ preservation, and immunosuppression have… read more here.
Keywords: heart transplant; organ preservation; heart; storage ... See more keywords
Vismodegib (V) for organ preservation for locally advanced (LA) orbital/periocular basal cell carcinoma (BCC).
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2020.38.15_suppl.10069
Abstract: 10069Background: LA BCC of the eye/lacrimal drainage system most often requires disfiguring radical surgery, possibly including exenteration. As an alternative to radical surgery, we evaluated opht... read more here.
Keywords: organ preservation; vismodegib organ; preservation locally; bcc ... See more keywords
Organ Preservation in Patients With Rectal Adenocarcinoma Treated With Total Neoadjuvant Therapy
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.22.00032
Abstract: PURPOSE Prospective data on the efficacy of a watch-and-wait strategy to achieve organ preservation in patients with locally advanced rectal cancer treated with total neoadjuvant therapy are limited. METHODS In this prospective, randomized phase II… read more here.
Keywords: free survival; neoadjuvant therapy; survival; organ preservation ... See more keywords
Rectal Gastrointestinal Stromal Tumor (GIST) in the Era of Imatinib: Organ Preservation and Improved Oncologic Outcome
Sign Up to like & getrecommendations! Published in 2017 at "Annals of Surgical Oncology"
DOI: 10.1245/s10434-017-6087-9
Abstract: BackgroundApproximately 5% of gastrointestinal stromal tumors (GISTs) originate in the rectum, and historically, radical resection was commonly performed. Little is known about the outcome for rectal GIST in the era of imatinib.MethodsUsing a prospectively maintained… read more here.
Keywords: organ preservation; era; gastrointestinal stromal; gist ... See more keywords
Adoption of Organ Preservation and Surgeon Variability for Patients with Rectal Cancer Does Not Correlate with Worse Survival
Sign Up to like & getrecommendations! Published in 2021 at "Annals of Surgical Oncology"
DOI: 10.1245/s10434-021-10877-3
Abstract: Watch-and-wait is variably adopted by surgeons and the impact of this on outcomes is unknown. We compared the disease-free survival and organ preservation rates of locally advanced rectal cancer patients treated by expert colorectal surgeons… read more here.
Keywords: organ preservation; survival; rectal cancer; surgeon ... See more keywords